Lumefantrine Impurity 14 CAS 2170653-95-7
| CAS No. | 2170653-95-7 |
| Molecular Formula | C30H32Cl3NO |
| Molecular Weight | 528.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lumefantrine Impurity 14 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lumefantrine Impurity 14 (CAS 2170653-95-7) is a certified pharmaceutical impurity reference standard with the molecular formula C30H32Cl3NO and a molecular weight of 528.94 g/mol.
Lumefantrine Impurity 14 (C30H32Cl3NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C30H32Cl3NO |
| Molecular Weight | 528.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Lumefantrine Standards
- (9E)-Lumefantrine (CAS 1456736-33-6)
- LUMEFANTRINE (CAS 204133-10-8)
- Lumefantrine Impurity 1 (CAS 1331642-68-2)
- Lumefantrine (CAS 82186-77-4)
- Lumefantrine-d9 (Benflumetol-d9) (CAS 2477594-24-2)
- Lumefantrine D18 (CAS 1185240-53-2)
- Lumefantrine impurity 7 (CAS CATO-C4X-24267)
- Lumefantrine Impurity 6 (CAS 355841-11-1)
Recommended Standards
- ((2-Chloro-6-(methoxymethoxy)-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalen-1-yl)ethynyl)triisopropylsilane (CAS 2771460-20-7)
- (E)-1,2-bis(4-dodecylthiophen-2-yl)ethene (CAS 306769-54-0)
- PSB 603 (CAS 1092351-10-4)
- AP 26113 (CAS 1197958-12-5)
- Imatinib Impurity 9 (CAS CATO-C4X-10689)
- Ensifentrine impurity (CAS 4359-64-2)
- Allopurinol EP Impurity D (CAS 6994-25-8)
- 2,3,4,9-Tetrahydro-1H-pyrido[3,4-b]indol-1-one (CAS 17952-82-8)
- 2,5-Di(2H-tetrazol-5-yl)terephthalic acid (CAS 2417761-51-2)
- 2-((3,4,4-Trifluorobut-3-en-1-yl)thio)-4,5-dihydro-1H-imidazole hydrobromide (CAS 318949-45-0)
- Mocetinostat, 98% (CAS 726169-73-9)
- 1-(benzo[d][1,3]dioxol-5-ylmethyl)-4-nitrosopiperazine (CAS CATO-C3D-262459)
- (2E)-1,3-Bis(2,5-Dimethoxyphenyl)prop-2-en-1-one (CAS 219298-68-7)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
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