5-Chloro-3-methyl-1,2,4-thiadiazole CAS 21734-85-0
| CAS No. | 21734-85-0 |
| Molecular Formula | C3H3ClN2S |
| Molecular Weight | 134.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-3-methyl-1,2,4-thiadiazole (CAS 21734-85-0) is a high-purity analytical reference standard with the molecular formula C3H3ClN2S and a molecular weight of 134.59 g/mol.
The molecular framework of 5-Chloro-3-methyl-1,2,4-thiadiazole (C3H3ClN2S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C3H3ClN2S |
| Molecular Weight | 134.59 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-chloro-5-methyl-1,2,4-thiadiazole (CAS 1393584-82-1)
- 2-Chloro-5-methyl-1,3,4-thiadiazole (CAS 53645-94-6)
- 5-Chloro-4-methyl-1,2,3-thiadiazole (CAS 53645-99-1)
- 4-Chloro-2-methyltetrahydro-2H-pyran (CAS 116131-46-5)
- 5-Chloro-3-methyl-2-pentanone (CAS 1187-81-1)
- 4-chloro-3,3-dimethylbutan-2-one (CAS 13104-53-5)
- 2-Chloro-3,3-dimethylbutanal (CAS 13422-65-6)
- (S)-1-Chloro-5-hexen-2-ol (CAS 1374009-33-2)
Recommended Standards
- 2-(Chloromethyl)-1,3,4-thiadiazole (CAS 1823233-50-6)
- 5-Chlorothiazol-2-amine (CAS 41663-73-4)
- 3-(chloromethyl)-1,2,5-thiadiazole (CAS 16311-47-0)
- 5-Chlorohexan-2-one (CAS 102438-65-3)
- 4-Amino-N-methyl-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide (CAS 51543-31-8)
- tert-Butyl 4-(2-chloronicotinoyl)-2-methylpiperazine-1-carboxylate (CAS 1353978-39-8)
- N-(2-chloro-4-methylphenyl)-2,2-difluoroacetamide (CAS 326006-54-6)
- (1-(2-Methoxyphenyl)-1H-pyrazol-4-yl)boronic acid (CAS 2225172-55-2)
- 1-Bromo-4-(pentafluoroethyl)benzene (CAS 206560-66-9)
- 1-Methyl-1-(1-methylpyrrolidin-3-yl)thiourea (CAS 473707-15-2)
- 7-(Diethylamino)-3-((4-ethylphenyl)sulfonyl)-6-fluoro-1-propylquinolin-4(1H)-one (CAS 892770-39-7)
- (S)-1-(tert-Butoxycarbonyl)-2-(2-methylbenzyl)pyrrolidine-2-carboxylic acid (CAS 1217669-63-0)
- N-Benzyl-5-(tert-butyl)-6-chloropyrazine-2-carboxamide (CAS 1391524-48-3)
- Exenatide Acetate (CAS 141732-76-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com