5-Chloro-4-methyl-1,2,3-thiadiazole CAS 53645-99-1
| CAS No. | 53645-99-1 |
| Molecular Formula | C3H3ClN2S |
| Molecular Weight | 134.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 5-Chloro-4-methyl-1,2,3-thiadiazole (C3H3ClN2S) is characterized by a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
5-Chloro-4-methyl-1,2,3-thiadiazole (CAS 53645-99-1) is a high-purity analytical reference standard with the molecular formula C3H3ClN2S and a molecular weight of 134.59 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Chloro-4-methyl-1,2,3-thiadiazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C3H3ClN2S |
| Molecular Weight | 134.59 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-chloro-5-methyl-1,2,4-thiadiazole (CAS 1393584-82-1)
- 2-Chloro-5-methyl-1,3,4-thiadiazole (CAS 53645-94-6)
- 5-Chloro-3-methyl-1,2,4-thiadiazole (CAS 21734-85-0)
- 4-Chloro-2-methyltetrahydro-2H-pyran (CAS 116131-46-5)
- 5-Chloro-3-methyl-2-pentanone (CAS 1187-81-1)
- 4-chloro-3,3-dimethylbutan-2-one (CAS 13104-53-5)
- 2-Chloro-3,3-dimethylbutanal (CAS 13422-65-6)
- (S)-1-Chloro-5-hexen-2-ol (CAS 1374009-33-2)
Recommended Standards
- 5-Chlorothiazol-2-amine (CAS 41663-73-4)
- 5-Chlorohexan-2-one (CAS 102438-65-3)
- 2-(Chloromethyl)-1,3,4-thiadiazole (CAS 1823233-50-6)
- 1-Chlorohex-5-en-2-ol (CAS 10293-98-8)
- Benzyl(benzylsulfamoyl)amine (CAS 42731-71-5)
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- 1-Amino-2-(phenylethynyl)anthracene-9,10-dione (CAS 115057-71-1)
- 2-(2-Chloroacetamido)-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxamide (CAS 519016-70-7)
- Mcpa-Methyl Ester (CAS 2436-73-9)
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- 2-Chloro-5-(isobutyramidomethyl)benzoic acid (CAS 1415090-17-3)
- [y-Glu3]-Semaglutide Impurity 135 (CAS CATO-C4X-2226135)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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