2-((5-Chloro-2-nitro-4-(trifluoromethyl)phenyl)thio)-N-mesitylacetamide CAS 217490-34-1
| CAS No. | 217490-34-1 |
| Molecular Formula | C18H16ClF3N2O3S |
| Molecular Weight | 432.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-((5-Chloro-2-nitro-4-(trifluoromethyl)phenyl)thio)-N-mesitylacetamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-((5-Chloro-2-nitro-4-(trifluoromethyl)phenyl)thio)-N-mesitylacetamide (CAS 217490-34-1), molecular formula C18H16ClF3N2O3S and molecular weight 432.84 g/mol, is a CATO reference standard with documented purity and traceability.
2-((5-Chloro-2-nitro-4-(trifluoromethyl)phenyl)thio)-N-mesitylacetamide (C18H16ClF3N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-((5-Chloro-2-nitro-4-(trifluoromethyl)phenyl)thio)-N-mesitylacetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16ClF3N2O3S |
| Molecular Weight | 432.84 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-Chloro-N-(3-cyano-4-((3-(trifluoromethyl)phenyl)thio)phenyl)benzamide (CAS 477866-68-5)
- 6-Chloro-2-(4-methoxyphenyl)-1-((3-(trifluoromethyl)benzyl)oxy)-1H-benzo[d]imidazole (CAS 329234-91-5)
- 6-Chloro-2-(4-methoxyphenyl)-1-((4-(trifluoromethyl)benzyl)oxy)-1H-benzo[d]imidazole (CAS 329234-93-7)
- 8-Benzyl-4-(4-chloro-2-fluorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326813-69-7)
- 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-methyl-N-(thiophen-2-ylmethyl)-1H-imidazole-5-carboxamide (CAS 339278-18-1)
- 7-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-methyl-2-thioxo-2,3,5,6,7,8-hexahydropyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4(1H)-one (CAS 321430-49-3)
- [4-Chloro-3-(4-ethoxybenzyl)phenyl][(3aS,5R,6S,6aS)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl]methanone (CAS 1103738-30-2)
- 5-((2-Chloro-6-fluorobenzyl)thio)-2-ethyl-8,9-dimethoxy-[1,2,4]triazolo[1,5-c]quinazoline (CAS 1221715-37-2)
Recommended Standards
- 1-(2-Chlorobenzenesulfonyl)-N-[3-(trifluoromethyl)phenyl]pyrrolidine-2-carboxamide (CAS 317377-92-7)
- Ethyl (2E)-2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-3-[(4-methoxyphenyl)amino]prop-2-enoate (CAS 338422-78-9)
- 1-((4-Chlorophenyl)sulfonyl)-N-(3-(trifluoromethyl)phenyl)pyrrolidine-2-carboxamide (CAS 317377-82-5)
- N-(4-chlorophenyl)-1-((3-(trifluoromethyl)phenyl)sulfonyl)pyrrolidine-2-carboxamide (CAS 317822-03-0)
- 5-Bromo-4-chloro-6-((4-methoxybenzyl)oxy)pyrimidine (CAS 1325694-78-7)
- 1-(2,3-Dihydro-1H-inden-2-yl)ethanone (CAS 33982-85-3)
- 4′-Methylbiphenyl-4-sulfonyl chloride (CAS 101366-51-2)
- 1,1'-(Butane-1,1-diylbis(azanediyl))bis(anthracene-9,10-dione) (CAS 88960-29-6)
- 4-((5H-Pyrrolo[3,2-d]pyrimidin-4-yl)oxy)-2-chloroaniline (CAS 919278-23-2)
- 2,4,6-Trichlorobenzothioamide (CAS 91979-32-7)
- 3-(Cyclopropylmethoxy)-5-isopropylphenol (CAS 1243387-12-3)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618414-35-0)
- (3-Aminopiperidin-1-yl)(3,5-dimethylisoxazol-4-yl)methanone (CAS 1249154-04-8)
- Semaglutide Impurity 140 (CAS CATO-C4X-2226140)
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