Fenofibrate EP Impurity G CAS 217636-48-1
| CAS No. | 217636-48-1 |
| Molecular Formula | C24H27ClO6 |
| Molecular Weight | 446.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Fenofibrate EP Impurity G is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Fenofibrate EP Impurity G (CAS 217636-48-1, C24H27ClO6) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution, Fenofibrate EP Impurity G is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 446.92 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fenofibrate EP Impurity G under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H27ClO6 |
| Molecular Weight | 446.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | Cl-containing |
Related Fenofibrate Standards
- Fenofibrate Impurity 21 (CAS CATO-C4X-101821)
- Fenofibrate Impurity 20 (CAS 60318-63-0)
- Fenofibrate Impurity 9 (CAS CATO-C4X-16439)
- Fenofibrate Dihydro Impurity (CAS 61001-99-8)
- Fenofibrate Impurity 10 (CAS CATO-C4X-164310)
- Fenofibrate (CAS 49562-28-9)
- Fenofibrate Impurity 17 (CAS CATO-C4X-101817)
- Fenofibrate Impurity 18 (CAS CATO-C4X-101818)
Recommended Standards
- 4,6-Dibromo-2-(4-bromophenyl)benzo[d]oxazol-5-amine (CAS 577768-91-3)
- Cetirizine Impurity 16 (CAS CATO-C4X-158216)
- 4,6-Dibromo-2-(3-bromophenyl)benzo[d]oxazol-5-amine (CAS 637302-92-2)
- Cetirizine impurity 31 (CAS CATO-C4X-158231)
- Limaprost Impurity 8 (CAS CATO-C4X-21458)
- Testosterone EP Impurity B (CAS 972-46-3)
- Erlotinib Impurity 85 (CAS CATO-C4X-106985)
- 4-((4-Isopropylphenyl)amino)-4-oxobutanoic acid (CAS 387359-18-4)
- 1-(4-Fluorophenyl)-2-hydroxy-4-[4-(2-methoxyphenyl)-1-piperazinyl]-1-butanone (CAS 51037-51-5)
- Methyl 1-isopropyl-1H-imidazole-2-carboxylate (CAS 1420885-48-8)
- 3,5-Difluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline (CAS 2657617-95-1)
- 1-(Cyclopent-1-en-1-yl)-1H-imidazole (CAS 201656-00-0)
- 1-Chloro-2,3,5,6-tetrafluoro-4-(trifluoromethoxy)benzene (CAS 1417569-17-5)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com