2-Hydroxy-3,17β-O-bis(methoxymethyl)estradiol CAS 217792-89-7

Purity 97%+In StockPharmaceutical Standards
CAS No.217792-89-7
Molecular FormulaC22H32O5
Molecular Weight376.49 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Hydroxy-3,17β-O-bis(methoxymethyl)estradiol CAS 217792-89-7 chemical structure

Description

The occurrence of 2-Hydroxy-3,17β-O-bis(methoxymethyl)estradiol is closely related to a flavonoid core, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 2-Hydroxy-3,17β-O-bis(methoxymethyl)estradiol (CAS 217792-89-7), a certified reference material (molecular formula C22H32O5, MW 376.49 g/mol) for analytical method development and quality control.

Based on its molecular formula C22H32O5, 2-Hydroxy-3,17β-O-bis(methoxymethyl)estradiol contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 376.49 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC22H32O5
Molecular Weight376.49 g/mol
AppearanceOff-white to pale yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2019

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