5-Chloro-2-nitrobenzenesulfonyl chloride CAS 21792-87-0
| CAS No. | 21792-87-0 |
| Molecular Formula | C6H3Cl2NO4S |
| Molecular Weight | 256.06 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 256.06 g/mol gives 5-Chloro-2-nitrobenzenesulfonyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-2-nitrobenzenesulfonyl chloride (CAS 21792-87-0) is a high-purity analytical reference standard with the molecular formula C6H3Cl2NO4S and a molecular weight of 256.06 g/mol.
The molecular framework of 5-Chloro-2-nitrobenzenesulfonyl chloride (C6H3Cl2NO4S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-Chloro-2-nitrobenzenesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H3Cl2NO4S |
| Molecular Weight | 256.06 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 2-Chloro-3-nitrobenzenesulfonyl chloride (CAS 15945-25-2)
- 2-Chloro-6-nitrobenzene-1-sulfonyl chloride (CAS 17970-75-1)
- 2-Chloro-4-nitrobenzenesulfonyl Chloride (CAS 20201-03-0)
- 2-Chloro-5-(chlorosulfonyl)nicotinic acid (CAS 476156-65-7)
- 2-Chloro-5-nitrobenzenesulfonyl Chloride (CAS 4533-95-3)
- 3-Chloro-2-nitrobenzenesulfonyl chloride (CAS 78846-40-9)
- 3-Chloro-4-nitrobenzenesulfonyl Chloride (CAS 64835-30-9)
- 3-Chloro-5-nitrobenzenesulfonyl chloride (CAS 953891-33-3)
Recommended Standards
- 5-Bromo-7-methylpyrazolo[1,5-a]pyrimidine-3-carboxylic acid (CAS 2306278-39-5)
- 6-Bromo-1-methyl-4-nitro-1H-benzo[d]imidazole (CAS 713530-59-7)
- 5-Bromo-1-methyl-1H-pyrazolo[4,3-b]pyridine-7-carboxylic acid (CAS 2090302-28-4)
- 6-bromo-2-methoxy-pyrazolo[1,5-a]pyrimidine-3-carbaldehyde (CAS 2092361-66-3)
- 1,4-Bis((1H-pyrazol-4-yl)ethynyl)benzene (CAS 1616862-09-9)
- Ethyl Indane-5-carboxylate (CAS 105640-11-7)
- 1-Hexyl-1h-1,2,3-triazol-4-amine (CAS 1516161-20-8)
- 5,7-Dimethylchroman-4-amine (CAS 749829-86-5)
- Tert-butyl 2-(4-morpholinophenyl)hydrazine-1-carboxylate (CAS 1414958-27-2)
- ((4-Formyl-1-phenyl-1H-imidazol-5-yl)selanyl)methyl acetate (CAS 62260-54-2)
- 3-(Trifluoromethyl)-4,5-dihydro-1H-indazol-6(7H)-one (CAS 944896-15-5)
- diethyl 2-[[(6-chloro-3-pyridyl)amino]methylene]propanedioate (CAS 66093-10-5)
- 3-Cyclopropoxy-5-methoxypicolinonitrile (CAS 1243405-65-3)
- His-Cyclic-Semaglutide (CAS CATO-C4X-2226182)
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