Posaconazole Impurity 267 CAS 2180759-84-4
| CAS No. | 2180759-84-4 |
| Molecular Formula | 2*C37H42F2N8O4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Posaconazole Impurity 267 (CAS 2180759-84-4) is a certified pharmaceutical impurity reference standard with the molecular formula C37H42F2N8O4 and a molecular weight of 700.79 g/mol.
Structurally, Posaconazole Impurity 267 (C37H42F2N8O4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 20.0, corresponding to approximately 20 ring(s) or double-bond equivalent(s). With a molecular weight of 700.79 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Posaconazole Impurity 267 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | 2*C37H42F2N8O4 |
| Molecular Weight | 700.79 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Posaconazole Standards
- Posaconazole Impurity 25 (CAS 1042398-26-4)
- Posaconazole Impurity 112 (CAS 110931-77-6)
- Posaconazole Impurity 111 (CAS 112559-81-6)
- Posaconazole-d4 (CAS 1133712-26-1)
- Posaconazole Impurity 84 (CAS 122151-32-0)
- Posaconazole Impurity 115 (CAS 122151-38-6)
- Posaconazole Impurity 67(R,S,R,R) (CAS 1229428-89-0)
- Posaconazole Impurity 22(R,S,S,R) (CAS 1229428-90-3)
Recommended Standards
- Cefodizime Impurity 6 (CAS 97180-26-2)
- Levocarnitine Impurity 18 (CAS 84367-31-7)
- Mycophenolic Acid Impurity 9 (CAS CATO-C4X-21229)
- 898-55-5 Benzene, 1,1'-cyclohexylidenebis[4-methoxy- DTXSID80364233 (CAS 898-55-5)
- 4-Chloro-5-fluoropicolinic acid (CAS 1060802-35-8)
- 2-(1H-pyrrol-3-yl)acetic acid (CAS 86688-96-2)
- 1-(3-Chloro-4-methoxyphenyl)-5-oxopyrrolidine-3-carboxylic acid (CAS 63674-98-6)
- DL-Phenylalanine Methyl Ester (CAS 15028-44-1)
- 2-Bromo-3-methyl-1-benzenesulfonyl Chloride (CAS 1261566-57-7)
- Tirzepatide Impurity 51 (CAS CATO-C4X-324051)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com