Posaconazole Impurity 112 CAS 110931-77-6
| CAS No. | 110931-77-6 |
| Molecular Formula | C10H8F2O3 |
| Molecular Weight | 214.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Posaconazole Impurity 112 (C10H8F2O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 214.17 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Posaconazole Impurity 112 (CAS 110931-77-6), a pharmacopoeial impurity reference standard (molecular formula C10H8F2O3, MW 214.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Posaconazole Impurity 112 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8F2O3 |
| Molecular Weight | 214.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1988 |
| Halogen Content | F-containing |
Related Posaconazole Standards
- Posaconazole Impurity 174 (CAS 2169241-14-7)
- Posaconazole Impurity 175 (CAS 169265-99-0)
- Posaconazole Impurity 164 (CAS CATO-C4X-1208164)
- Posaconazole Impurity 66 (CAS 1428118-25-5)
- Posaconazole Impurity 119 (CAS 2243786-03-8)
- Posaconazole impurity 219 (CAS CATO-C4X-1208219)
- Posaconazole Impurity 262(R/S Mixture) (CAS CATO-C4X-1208262)
- Posaconazole Impurity 86 (CAS 170985-84-9)
Recommended Standards
- 478162-62-8 4-(2,6-Difluorophenyl)-4-oxobutanoic acid DTXSID70620936 (CAS 478162-62-8)
- 1-(4-Nitrophenyl)-1H-pyrazole-4-carbonitrile (CAS 102539-56-0)
- s-Indacene-1,3,5,7(2H,6H)-tetrone (CAS 53910-13-7)
- 3-Cyano-4-oxo-1,4-dihydroquinoline-6-carboxylic acid (CAS 1056941-85-5)
- N-((S)-4-amino-1-carboxy-4-oxobutyl)-N-glycylglycyl-D-glutamine (CAS CATO-CPTD789027)
- Posaconazole Impurity 120 (CAS CATO-C4X-1208120)
- Empagliflozin impurity 215 (CAS 2452301-37-8)
- 2,2,2-Trifluoro-N-(4-(3-fluoro-4-methoxyphenyl)piperidin-3-yl)acetamide (CAS 1432680-28-8)
- 951886-18-3 3-Chloro-3'-fluoro-4'-methylbenzophenone MFCD09801617 (CAS 951886-18-3)
- ((2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-(phosphonooxy)tetrahydrofuran-2-yl)methyl dihydrogen phosphate (CAS 4682-43-3)
- (4-Ethynylphenyl)(phenyl)methanone (CAS 119754-17-5)
- 3-(4-Aminophenoxy)-N-methylbenzamide (CAS 284462-56-2)
- 5-Iodo-1,1,1-trifluoropentane (CAS 352-60-3)
- Acetyl-Exenatide trifluoroacetate salt (CAS 305815-28-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com