Prucalopride Impurity 24 CAS 2181480-01-1
| CAS No. | 2181480-01-1 |
| Molecular Formula | C20H28ClN3O4 |
| Molecular Weight | 409.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Prucalopride Impurity 24 (CAS 2181480-01-1) is a certified pharmaceutical impurity reference standard with the molecular formula C20H28ClN3O4 and a molecular weight of 409.91 g/mol.
Prucalopride Impurity 24 (C20H28ClN3O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H28ClN3O4 |
| Molecular Weight | 409.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Prucalopride Standards
- Prucalopride Impurity 22 (CAS CATO-C4X-103822)
- Prucalopride Impurity 41（DP-4） (CAS 1900715-95-8)
- Prucalopride Impurity 40（DP-3） (CAS 1900715-94-7)
- Prucalopride Impurity 45 (CAS CATO-C4X-103845)
- Prucalopride Impurity 17 (CAS CATO-C4X-103817)
- Prucalopride Impurity N11 (CAS 748788-39-8)
- Prucalopride Impurity 44 (CAS CATO-C4X-103844)
- Prucalopride Impurity 21 (CAS 2636673-48-6)
Recommended Standards
- N-(4-Chloro-2-phenoxyphenyl)-N-[[2-(1-methylethoxy)phenyl]methyl]-acetamide (CAS 220551-79-1)
- N-(5-(5-Chlorothiophene-2-carbonyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)thiophene-3-carboxamide (CAS 1428363-91-0)
- Ethyl 3-(N-(5-chloro-2-methylphenyl)sulfamoyl)benzo[b]thiophene-2-carboxylate (CAS 932303-46-3)
- 1-(Bromomethyl)-2-iodo-3-nitro-5-(trifluoromethyl)benzene (CAS 943917-58-6)
- Tiotropium impurity 44 (CAS 4408-82-6)
- Ciclosporin EP Impurity C (CAS 59865-16-6)
- Rimegepant Impurity 52 DiHCl (CAS CATO-C4X-248752)
- 2-(5-Chlorothiophen-2-yl)-3-methylbutan-2-ol (CAS 1379317-23-3)
- 2-Bromo-4-(3-methoxy-4-methylphenyl)thiazole (CAS 886367-67-5)
- 1,4,4-Trimethyl-L-proline (CAS 1443245-02-0)
- [9]Cycloparaphenylene (CAS 1092522-74-1)
- 2-((4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-methoxyphenyl)acetamide (CAS 626205-01-4)
- 1-(2-Chlorophenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid (CAS 948293-88-7)
- Epidermal Growth Factor Receptor Peptide (985-996) (CAS 96249-43-3)
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