tert-Butyl (3-hydroxy-1-phenylpropyl)carbamate CAS 218449-48-0
| CAS No. | 218449-48-0 |
| Molecular Formula | C14H21NO3 |
| Molecular Weight | 251.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies tert-Butyl (3-hydroxy-1-phenylpropyl)carbamate (CAS 218449-48-0), a certified reference material (molecular formula C14H21NO3, MW 251.32 g/mol) for analytical method development and quality control.
The molecular framework of tert-Butyl (3-hydroxy-1-phenylpropyl)carbamate (C14H21NO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H21NO3 |
| Molecular Weight | 251.32 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl (2s,3r)-3-amino-2-hydroxy-4-phenylbutanoate (CAS 204587-95-1)
- tert-Butyl (3-hydroxy-3-phenylpropyl)carbamate (CAS 257892-43-6)
- Tert-butyl (2-hydroxy-2-phenylethyl)(methyl)carbamate (CAS 77184-09-9)
- Tert-butyl (4-(hydroxymethyl)benzyl)(methyl)carbamate (CAS 774238-90-3)
- Ethyl 2-(4-fluorophenoxy)ethanecarboximidate hydrochloride (CAS 1029989-42-1)
- 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-sulfonamide (CAS 1083326-26-4)
- tert-Butyl (3-acetyl-5-chlorobenzyl)carbamate (CAS 1393546-04-7)
- Chlorbenside-Sulfoxide (CAS 7047-28-1)
- 5-[2-(4-Methoxyanilino)vinyl]-3-phenyl-4-isoxazolecarbonitrile (CAS 303995-74-6)
- 2-(5-Amino-3-ethyl-4-(methylsulfonyl)-1H-pyrazol-1-yl)ethanol (CAS 1708436-67-2)
- Etomidate Impurity 44 (CAS 39096-80-5)
- 5-Bromo-4-chloro-6-(difluoromethyl)pyrimidine (CAS 677777-61-6)
- Ambroxol Impurity 57 (CAS CATO-C4X-108557)
- Semaglutide Impurity 10 (CAS CATO-C4X-222610)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com