Tert-butyl (2-(3,4-difluorophenyl)-2-hydroxyethyl)carbamate CAS 218449-63-9
| CAS No. | 218449-63-9 |
| Molecular Formula | C13H17F2NO3 |
| Molecular Weight | 273.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Tert-butyl (2-(3,4-difluorophenyl)-2-hydroxyethyl)carbamate (C13H17F2NO3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 273.28 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Tert-butyl (2-(3,4-difluorophenyl)-2-hydroxyethyl)carbamate (CAS 218449-63-9) is a high-purity analytical reference standard with the molecular formula C13H17F2NO3 and a molecular weight of 273.28 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Tert-butyl (2-(3,4-difluorophenyl)-2-hydroxyethyl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H17F2NO3 |
| Molecular Weight | 273.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- Tert-butyl (2-(2,4-difluorophenyl)-2-hydroxyethyl)carbamate (CAS 939757-31-0)
- Tert-butyl (2-(3,5-difluorophenyl)-2-hydroxyethyl)carbamate (CAS 333388-01-5)
- Pyridoxine /Vitamin B6 Impurity C93 (CAS 5223-10-9)
- tert-Butyl (2,4-difluoro-3-(1-hydroxyethyl)phenyl)carbamate (CAS 2110320-47-1)
- 2-Bromo-5-methoxy-N-(2-(thiophen-3-yl)benzyl)benzamide (CAS 1796947-13-1)
- 1-(4-(Trifluoromethyl)phenyl)prop-2-yn-1-one (CAS 704889-22-5)
- 1-Phenyl-1H-1,2,3-triazole-4-ethanol (CAS 1248403-05-5)
- 1-Aminopyridin-1-ium-4-carboxylate (CAS 31775-03-8)
- 2-Amino-N-phenylethanesulfonamide (CAS 25840-61-3)
- N-{5H,6H,7H,8H-imidazo[1,2-a]pyridin-6-ylmethyl}methanesulfonamide (CAS 1803611-79-1)
- Avibactam Impurity 34（2S,5S） (CAS 2085372-13-8（free base）)
- N-(1-cyano-2-methylpropyl)benzamide (CAS 91565-90-1)
- 2-Amino-4-phenylpyrimidine-5-carbonitrile (CAS 264927-84-6)
- Semaglutide impurity 54 (CAS CATO-C4X-222654)
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