N-(2-Amino-5-chloro-4-fluoro-phenyl)-acetamide CAS 218456-61-2

Purity 97%+In StockPharmaceutical Standards
CAS No.218456-61-2
Molecular FormulaC8H8ClFN2O
Molecular Weight202.61 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2-Amino-5-chloro-4-fluoro-phenyl)-acetamide CAS 218456-61-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(2-Amino-5-chloro-4-fluoro-phenyl)-acetamide.

N-(2-Amino-5-chloro-4-fluoro-phenyl)-acetamide (CAS 218456-61-2), molecular formula C8H8ClFN2O and molecular weight 202.61 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-(2-Amino-5-chloro-4-fluoro-phenyl)-acetamide (C8H8ClFN2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

CATO manufactures N-(2-Amino-5-chloro-4-fluoro-phenyl)-acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H8ClFN2O
Molecular Weight202.61 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2019
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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Why CATO?