Sitagliptin Impurity 26 CAS 218609-00-8

Purity 97%+In StockPharmaceutical Standards
CAS No.218609-00-8
Molecular FormulaC15H20FNO4
Molecular Weight297.32 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Sitagliptin Impurity 26 CAS 218609-00-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 297.32 g/mol gives Sitagliptin Impurity 26 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Sitagliptin Impurity 26 (CAS 218609-00-8), molecular formula C15H20FNO4 and molecular weight 297.32 g/mol, is a CATO reference standard with documented purity and traceability.

Sitagliptin Impurity 26 (C15H20FNO4) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures Sitagliptin Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC15H20FNO4
Molecular Weight297.32 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2019
Halogen ContentF-containing
Nitrogen Atoms1

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