2-（丙-2-基-1-基氧基）-4-（3-（三氟甲基）-3<I>H</I>-重氮基-3-基）苯甲酸 CAS 2187374-12-3
| CAS No. | 2187374-12-3 |
| Molecular Formula | C12H7F3N2O3 |
| Molecular Weight | 284.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-（丙-2-基-1-基氧基）-4-（3-（三氟甲基）-3<I>H</I>-重氮基-3-基）苯甲酸.
2-（丙-2-基-1-基氧基）-4-（3-（三氟甲基）-3<I>H</I>-重氮基-3-基）苯甲酸 (CAS 2187374-12-3), molecular formula C12H7F3N2O3 and molecular weight 284.19 g/mol, is a CATO reference standard with documented purity and traceability.
2-（丙-2-基-1-基氧基）-4-（3-（三氟甲基）-3<I>H</I>-重氮基-3-基）苯甲酸 (C12H7F3N2O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-（丙-2-基-1-基氧基）-4-（3-（三氟甲基）-3<I>H</I>-重氮基-3-基）苯甲酸 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H7F3N2O3 |
| Molecular Weight | 284.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
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