Erythromycin EP Impurity D CAS 23893-13-2
| CAS No. | 23893-13-2 |
| Molecular Formula | C37H65NO12 |
| Molecular Weight | 715.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Erythromycin EP Impurity D (CAS 23893-13-2, C37H65NO12) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Erythromycin EP Impurity D (C37H65NO12) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Erythromycin EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C37H65NO12 |
| Molecular Weight | 715.91 g/mol |
| Purity | >90% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
Related Erythromycin Standards
- Erythromycin EP Impurity E (CAS 33396-29-1)
- Erythromycin EP Impurity F (CAS 105882-69-7)
- Erythromycin Impurity 53 (CAS CATO-C4X-100153)
- Erythromycin B rearranged derivatives (CAS CATO-C4X-100170)
- Erythromycin C rearranged derivatives (CAS CATO-C4X-100171)
- Erythromycin thiocyanate impurity B rearranged derivative (CAS CATO-C4X-100174)
- Erythromycin B (CAS 527-75-3)
- Erythromycin EP Impurity B (CAS 992-62-1)
Recommended Standards
- 10,11-Anhydroerythromycin A (CAS 40554-78-7)
- (3S,3aR,6aS)-Hexahydrofuro[2,3-b]furan-3-ylcarbonyl Darunavir (CAS 1546918-97-1)
- Davercin impurity 1 (CAS CATO-C4X-34381)
- DPP48-Br (CAS 1454609-37-0)
- Betamethasone Valerate EP Impurity I (CAS 2802-10-0)
- Cilnidipine impurity 21 (CAS CATO-C4X-179621)
- Vonoprazan Impurity 160 (CAS 2514735-12-5)
- 1-Phenylpentane-1,4-dione (CAS 583-05-1)
- 3-(2,2-Dimethoxyethyl)-2-sulfanylideneimidazolidin-4-one (CAS 477889-52-4)
- Ethyl 2-bromo-3-oxo-3-phenylpropanoate (CAS 55919-47-6)
- 3-(Oxolane-2-amido)benzoic acid (CAS 669704-13-6)
- Cabozantinib Impurity 10 (CAS 98300-41-5)
- 4-Methyl-2-(piperidin-4-yl)pyrimidine-5-carboxamide dihydrochloride (CAS 1361116-31-5)
- Hepcidin/LEAP-1 (Human); Liver-Expressed Antimicrobial Peptide (CAS 342790-21-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com