Methyl 3-bromo-6-chloro-5-(dimethylamino)pyrazine-2-carboxylate CAS 21874-50-0
| CAS No. | 21874-50-0 |
| Molecular Formula | C8H9BrClN3O2 |
| Molecular Weight | 294.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 3-bromo-6-chloro-5-(dimethylamino)pyrazine-2-carboxylate.
Methyl 3-bromo-6-chloro-5-(dimethylamino)pyrazine-2-carboxylate (CAS 21874-50-0) is a high-purity analytical reference standard with the molecular formula C8H9BrClN3O2 and a molecular weight of 294.53 g/mol.
Structurally, Methyl 3-bromo-6-chloro-5-(dimethylamino)pyrazine-2-carboxylate (C8H9BrClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 294.53 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl 3-bromo-6-chloro-5-(dimethylamino)pyrazine-2-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H9BrClN3O2 |
| Molecular Weight | 294.53 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 3 |
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Recommended Standards
- Methyl 3-bromo-6-chloro-5-(ethylamino)pyrazine-2-carboxylate (CAS 21874-51-1)
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- 2-(Benzylsulfanyl)-6-[(E)-2-(4-methylphenyl)ethenyl]-4-[(Z)-2-(4-methylphenyl)ethenyl]pyridine-3-carbonitrile (CAS 303985-51-5)
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- 3-(4-Bromophenyl)-1-(4-chloro-3-fluorophenyl)propan-1-one (CAS 898761-64-3)
- Dotinurad Impurity 203 (CAS CATO-C4X-2494203)
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- N-Nitroso Valganciclovir (CAS CATO-C4X-177418)
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