Dotinurad Impurity 203 CAS CATO-C4X-2494203
| CAS No. | CATO-C4X-2494203 |
| Molecular Formula | C14H10ClNO2S |
| Molecular Weight | 291.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Dotinurad Impurity 203 (CAS CATO-C4X-2494203), a pharmacopoeial impurity reference standard (molecular formula C14H10ClNO2S, MW 291.75 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Dotinurad Impurity 203 (C14H10ClNO2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 291.75 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Dotinurad Impurity 203 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H10ClNO2S |
| Molecular Weight | 291.75 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dotinurad Standards
- Dotinurad Impurity 125 (CAS CATO-C4X-2494125)
- Dotinurad Impurity 45 (CAS CATO-C4X-249445)
- Dotinurad Impurity 61 (CAS 428458-98-4)
- Dotinurad Impurity 25 (CAS 2142685-21-8)
- Dotinurad Impurity 56 (CAS CATO-C4X-249456)
- Dotinurad Impurity 215 (CAS CATO-C4X-2494215)
- Dotinurad Impurity 212 (CAS CATO-C4X-2494212)
- Dotinurad Impurity 46 (CAS 19048-93-2)
Recommended Standards
- Ticagrelor impurity 104 (CAS CATO-C4X-1093104)
- 5-(1-(3-Chlorophenyl)-5-methyl-1H-pyrazol-4-yl)-4H-1,2,4-triazole-3-thiol (CAS 1019090-30-2)
- 4-[(4-chlorophenyl)methyl]-4H-thieno[3,2-b]pyrrole-5-carboxylic acid 924643-46-9 NS-04875 (CAS 924643-46-9)
- 2-{[4-(chloromethyl)-1,3-thiazol-2-yl]methyl}-1,2-dihydrophthalazin-1-one (CAS 1094436-42-6)
- Fluvastatin Impurity 19 (CAS CATO-C4X-165119)
- Fluconazole Impurity 41 (CAS CATO-C4X-101941)
- Pimecrolimus Impurity 11 (CAS CATO-C4X-173111)
- 3-Chloro-2-(dimethylamino)-9H-fluoren-9-one (CAS 7151-56-6)
- Dobutamine Impurity 15 (CAS 334947-74-9)
- Vazegepant Impurity 14 (CAS 928014-62-4)
- N-(2-Methylphenyl)formamide (CAS 94-69-9)
- N-Decanoyl-DL-homoserine lactone (CAS 106983-36-2)
- 34415-10-6 4-Pyrimidinecarboxylic acid, 1,6-dihydro-2-methyl-6-oxo- (9CI) 4-Pyrimidinecarboxylic acid, 6-hydroxy-2-methyl- 2-Methylorotic acid NSC 58348 (CAS 34415-10-6)
- Semaglutide impurity 43 (CAS CATO-C4X-222643)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com