Carbocisteine Impurity 54 TFA CAS 21885-10-9
| CAS No. | 21885-10-9 |
| Molecular Formula | C5H9NO4S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Carbocisteine Impurity 54 TFA (CAS 21885-10-9), a pharmacopoeial impurity reference standard (molecular formula C5H9NO4SC2HF3O2, MW 293.21 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Carbocisteine Impurity 54 TFA (C5H9NO4SC2HF3O2) is characterized by a carbohydrate-derived structure, an amide group, a sulfone group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C5H9NO4S C2HF3O2 |
| Molecular Weight | 293.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Carbocisteine Standards
- Carbocisteine (S)-S-Oxide (CAS 112246-66-9)
- Carbocisteine-13C3 (CAS 1391068-19-1)
- Carbocisteine Impurity 19 (CAS 14226-97-2)
- Carbocisteine Impurity 17 (CAS 15253-37-9)
- Carbocisteine Impurity 10 (CAS 1601460-92-7)
- Carbocisteine Impurity 13 (CAS 21301-10-0)
- Carbocisteine Impurity 11 (CAS 25515-73-5)
- Carbocisteine Impurity 4 TFA (Mixture of diastereomers) (CAS 25515-73-5（free base）)
Recommended Standards
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- Ethyl 3-(tetrahydrofuran-2-yl)-1H-1,2,4-triazole-5-carboxylate (CAS 1339790-16-7)
- Bis(2-phenylethyl)amine (CAS 6308-98-1)
- Tert-butyl N-[(1-imino-2,2-dimethyl-1-oxo-thiolan-3-yl)methyl]carbamate (CAS 2243512-11-8)
- 1-(Pyrrolidin-3-yl)urea hydrochloride (CAS 1423032-78-3)
- 1,3-Diphenyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid (CAS 24086-34-8)
- 2-(3-Butynyl)-1,3-dioxolane-2-ethanol (CAS 91798-92-4)
- Neuropeptide S (rat) (CAS 412938-75-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com