2-chloro-4-fluorophenyl 2,6-dichloroisonicotinate CAS 218928-46-2
| CAS No. | 218928-46-2 |
| Molecular Formula | C12H5Cl3FNO2 |
| Molecular Weight | 320.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-chloro-4-fluorophenyl 2,6-dichloroisonicotinate.
CATO supplies 2-chloro-4-fluorophenyl 2,6-dichloroisonicotinate (CAS 218928-46-2), a certified reference material (molecular formula C12H5Cl3FNO2, MW 320.53 g/mol) for analytical method development and quality control.
Structurally, 2-chloro-4-fluorophenyl 2,6-dichloroisonicotinate (C12H5Cl3FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 320.53 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-chloro-4-fluorophenyl 2,6-dichloroisonicotinate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H5Cl3FNO2 |
| Molecular Weight | 320.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
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- Epistane Discontinued See T344425 (CAS 4267-80-5)
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- 5-Pentadecylresorcinol (CAS 3158-56-3)
- 5-(2-Bromophenyl)-4H-1,2,4-triazole-3-carboxylic acid (CAS 944906-67-6)
- Methyl 2-(chlorosulfonyl)cyclopent-1-ene-1-carboxylate (CAS 87631-72-9)
- 5-Bromo-7-methyl-1H-benzo[d][1,2,3]triazole (CAS 1354777-43-7)
- 6-(Trifluoromethyl)pyrazine-2-carbaldehyde (CAS 1197233-06-9)
- (3-Benzyl-3-azabicyclo[4.1.0]heptan-1-yl)methanol (CAS 309748-42-3)
- 1-Benzyl 4-methyl 3-fluoropiperidine-1,4-dicarboxylate (CAS 1303972-82-8)
- PG-9 Maleate (CAS 155649-00-6)
- 2,4-Dimethoxy-5-methylbenzaldehyde (CAS 7149-91-9)
- (1-(Pyrazin-2-yl)piperidin-3-yl)methanol (CAS 939986-03-5)
- Polymyxin B nonapeptide TFA (CAS 2220175-42-6)
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