4-chloro-3-methylbenzoyl chloride CAS 21900-24-3
| CAS No. | 21900-24-3 |
| Molecular Formula | C8H12Cl2O |
| Molecular Weight | 195.09 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-chloro-3-methylbenzoyl chloride (C8H12Cl2O) contains a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
4-chloro-3-methylbenzoyl chloride (CAS 21900-24-3), molecular formula C8H12Cl2O and molecular weight 195.09 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12Cl2O |
| Molecular Weight | 195.09 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Stable under recommended storage conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
Related chloro Standards
- 1253790-56-5 3-Chloro-3-cyclopentylpropionyl chloride SC-21652 (CAS 1253790-56-5)
- 2-chloro-1-(4-chlorophenyl)ethanone (CAS 937-20-2)
- 2-Chloro-5-(3-chloropropyl)thiophene (CAS 1250362-60-7)
- 2-Chloro-1-(3-chlorothiophen-2-yl)ethanone (CAS 62673-63-6)
- 2-Chloro-1-(5-chlorothiophen-2-yl)ethan-1-one (CAS 42445-55-6)
- 2-chloro-4-methylthiophene-3-carbonyl chloride (CAS 85345-23-9)
- 3-Chloro-4-methylthiophene-2-carbonyl chloride (CAS 690632-13-4)
- 2-Chloro-4-(chloromethoxy)-1-fluorobenzene (CAS 1507759-34-3)
Recommended Standards
- 5,7-dichloro-1H-benzimidazole (CAS 82326-55-4)
- 2,4-dichloro-5-methylbenzaldehyde (CAS 63525-12-2)
- 5466-43-3 AR-1I5628 dimethyl benzene-1,4-dicarboxylate; ethylene glycol; 2-(2-hydroxyethoxy)ethanol (CAS 5466-43-3)
- 2,3-dichloro-4-methyl-benzaldehyde (CAS 170879-71-7)
- 5-Methoxy-1,3-benzothiazol-2-amine (CAS 54346-87-1)
- (S)-(-)-1,1-Bis(4-methoxyphenyl)-3-methyl-1,2-butanediamine (CAS 148369-91-9)
- 2-(1-(Tert-butoxycarbonyl)azetidin-3-yl)-3-cyclobutylpropanoic acid (CAS 2227205-05-0)
- 4-(Pyrazin-2-yl)piperazine-1-sulfonamide (CAS 1281107-10-5)
- Sotagliflozin (CAS 1018899-04-1)
- 4-(Isopropylamino)phenylboronic Acid (CAS 219945-56-9)
- Hexahydropyrrolo[3,4-c]pyrrole-1,3-dione (CAS 1202067-90-0)
- Amlodipine Besylate EP Impurity H (CAS 318465-73-5)
- 2-(2-Methylcyclopentyl)ethyl oxazole-4-carboxylate (CAS 89724-27-6)
- Vasonatrin Peptide (VNP) trifluoroacetate salt (CAS 141676-35-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com