Bromfenac Impurity 41 CAS 2192334-72-6
| CAS No. | 2192334-72-6 |
| Molecular Formula | C30H18Br2N2O2 |
| Molecular Weight | 598.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Bromfenac Impurity 41 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Bromfenac Impurity 41 (CAS 2192334-72-6, C30H18Br2N2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Bromfenac Impurity 41 (C30H18Br2N2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C30H18Br2N2O2 |
| Molecular Weight | 598.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromfenac Standards
- Bromfenac Impurity 40 (CAS CATO-C4X-200240)
- Bromfenac Impurity 2 (CAS CATO-C4X-20022)
- Bromfenac Impurity 32 (CAS CATO-C4X-200232)
- Bromfenac Impurity 33 (CAS 1644279-16-2)
- Bromfenac Impurity 63 (CAS CATO-C4X-200263)
- Bromfenac Impurity N2 (CAS 1798431-98-7)
- Bromfenac Impurity 60 (CAS CATO-C4X-200260)
- Bromfenac Impurity 61 (CAS CATO-C4X-200261)
Recommended Standards
- Nonanedioic acid, polymer with 1,2-propanediol (CAS 29408-67-1)
- 3-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrrole-2-sulfonate (CAS 338406-93-2)
- N-(3,5-dichlorobenzyl)-2-(1,1,2,2,3,3,4,4,5,5,6,6,6-tridecafluorohexyl)benzamide (CAS 680213-80-3)
- 6,8-Dibromo-3,3-bis(((2-ethylhexyl)oxy)methyl)-3,4-dihydro-2H-thieno[3,4-b][1,4]dioxepine (CAS 700817-08-9)
- Silodosin Impurity 3 (CAS CATO-C4X-17543)
- Cariprazine Impurity 23 (CAS 1480744-25-9)
- Sotalol EP Impurity B HCl (CAS 5576-49-8)
- 3-(Benzyloxy)-1H-pyrazole-4-carboxylic acid (CAS 478968-57-9)
- N-((1-Isobutyl-1H-pyrazol-5-yl)methyl)-1,3-dimethyl-1H-pyrazol-5-amine hydrochloride (CAS 1856068-76-2)
- 4-(Dimethylamino)-N-isobutylbenzamide (CAS 851613-30-4)
- 2-((4-Amino-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(3,5-dimethoxyphenyl)acetamide (CAS 578758-45-9)
- Bisabolol Impurity 1 (CAS 76738-75-5)
- Methyl 6-bromo-1-methylindoline-4-carboxylate (CAS 1629879-87-3)
- D-Lys20-Tirzepatide (CAS CATO-CPTD788914)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com