Bromfenac Impurity 33 CAS 1644279-16-2
| CAS No. | 1644279-16-2 |
| Molecular Formula | C30H18Br2N2O3 |
| Molecular Weight | 614.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Bromfenac Impurity 33 (C30H18Br2N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Bromfenac Impurity 33 (CAS 1644279-16-2, C30H18Br2N2O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Bromfenac Impurity 33 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H18Br2N2O3 |
| Molecular Weight | 614.28 g/mol |
| Purity | >80% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 22.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromfenac Standards
- Bromfenac Impurity 2 (CAS CATO-C4X-20022)
- Bromfenac Impurity 32 (CAS CATO-C4X-200232)
- Bromfenac Impurity 63 (CAS CATO-C4X-200263)
- Bromfenac Impurity 40 (CAS CATO-C4X-200240)
- Bromfenac Impurity N2 (CAS 1798431-98-7)
- Bromfenac Impurity 41 (CAS 2192334-72-6)
- Bromfenac Impurity 60 (CAS CATO-C4X-200260)
- Bromfenac Impurity 61 (CAS CATO-C4X-200261)
Recommended Standards
- 4-tert-Butyldimethylsilyl-5-chloro-4a-hydroxy-6-(hydroxyimino)methyl Simvastatin (CAS 123852-22-2)
- 3-Chloro-2-{2-[(1E,3E)-2-(4-chlorobenzenesulfonyl)-3-{[(2,6-dichlorophenyl)methoxy]imino}prop-1-en-1-yl]hydrazin-1-yl}-5-(trifluoromethyl)pyridine (CAS 338407-65-1)
- 2-Methoxy-1,4-dioxane (CAS 20732-36-9)
- Montelukast Impurity 50 (CAS 1044705-96-5)
- Ketoprofen Impurity 94 (CAS CATO-C4X-147194)
- Ibrutinib Impurity 73 (CAS 2213398-76-4)
- Loxoprofen impurity 124 (CAS CATO-C4X-1488124)
- 4-(PRopane-1-sulfonyl)phenol (CAS 148038-16-8)
- 3-Benzylcyclobutanecarboxylic acid (CAS 66016-21-5)
- 5-bromo-4-chloropyrazolo[1,5-a]pyridine (CAS 1427415-74-4)
- H-D-Dap(Boc)-OMe (CAS 363191-25-7)
- 5-(benzyloxy)-2-(hydroxymethyl)-1-methyl-1,4-dihydropyridin-4-one (CAS 89539-51-5)
- Budesonide Impurity 36 (CAS 77017-20-0)
- Neuropeptide S (rat) (CAS 412938-75-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com