1-(4-Chlorobenzyl)-4-piperidone CAS 21937-61-1
| CAS No. | 21937-61-1 |
| Molecular Formula | C12H14ClNO |
| Molecular Weight | 223.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-(4-Chlorobenzyl)-4-piperidone (CAS 21937-61-1), molecular formula C12H14ClNO and molecular weight 223.70 g/mol, is a CATO reference standard with documented purity and traceability.
1-(4-Chlorobenzyl)-4-piperidone (C12H14ClNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14ClNO |
| Molecular Weight | 223.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzyl Standards
- n-(4-Chlorobenzyl)-3-methylbut-2-enamide (CAS 1252343-84-2)
- n-(2-Chlorobenzyl)-3-methylbut-2-enamide (CAS 1252522-45-4)
- 3-(4-Chlorobenzyl)-2-piperidone (CAS 1260763-19-6)
- 3-(2-Chlorobenzyl)-2-piperidone (CAS 1260766-37-7)
- 1-(2-Chlorobenzyl)pyrrolidine-3-carbaldehyde (CAS 1447962-27-7)
- 1-(3-Chlorobenzyl)piperidin-4-one (CAS 247206-81-1)
- (1-(4-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 321405-39-4)
- 1-(4-Chlorobenzyl)pyrrolidine-2,5-dione (CAS 91349-11-0)
Recommended Standards
- 1-(3-Chloropropyl)-3,4-dihydroquinolin-2(1H)-one (CAS 79145-37-2)
- 1-(4-Chlorophenyl)cyclopentanecarboxamide (CAS 84833-61-4)
- 2-(Tert-butyl)-4-chloro-5-methyl-7H-pyrrolo[2,3-d]pyrimidine (CAS 2306269-50-9)
- 1-(3-Chloro-4-methylphenyl)piperidin-4-one (CAS 938459-09-7)
- 1-azabicyclo[3.2.1]octane-5-carboxylic acid hydrochloride (CAS 119102-94-2)
- tert-Butyl (2S)-2-[(6-fluoro-1H-indol-3-yl)methyl]pyrrolidine-1-carboxylate (CAS 874774-56-8)
- 4,5-Difluoro-2-(methoxycarbonyl)phenylboronic acid (CAS 2096334-34-6)
- (3R,4R)-1-(tert-butoxycarbonyl)-4-(4-cyanophenyl)-3-fluoropyrrolidine-3-carboxylic acid (CAS 1835266-92-6)
- 3-(4-Chlorophenyl)-1-(6-chloropyridin-2-yl)-6-(trifluoromethyl)-1H-pyrazolo[4,3-b]pyridine (CAS 303152-01-4)
- 3,7-Dibromo-10-phenyl-10H-phenothiazine (CAS 89922-58-7)
- N4-(3-Bromophenyl)quinazoline-4,6,7-triamine (CAS 169205-87-2)
- 2-Hydroxy-5-methylbenzene-1-sulfonyl chloride (CAS 926219-97-8)
- Prostaglandin Impurity N2 (CAS 20897-91-0)
- Semaglutide Impurity 1(OtBu-Ste-D-γGlu(OtBu)-AEEA-AEEA-OH) (CAS CATO-C4X-22261)
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