4-[4-(3-Chloropropyl)-1-piperazinyl]-2-(1,1-dimethylethyl)-6-(trifluoromethyl)pyrimidine CAS 219600-00-7
| CAS No. | 219600-00-7 |
| Molecular Formula | C16H24ClF3N4 |
| Molecular Weight | 364.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 364.84 g/mol gives 4-[4-(3-Chloropropyl)-1-piperazinyl]-2-(1,1-dimethylethyl)-6-(trifluoromethyl)pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-[4-(3-Chloropropyl)-1-piperazinyl]-2-(1,1-dimethylethyl)-6-(trifluoromethyl)pyrimidine (CAS 219600-00-7), a certified reference material (molecular formula C16H24ClF3N4, MW 364.84 g/mol) for analytical method development and quality control.
4-[4-(3-Chloropropyl)-1-piperazinyl]-2-(1,1-dimethylethyl)-6-(trifluoromethyl)pyrimidine (C16H24ClF3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-[4-(3-Chloropropyl)-1-piperazinyl]-2-(1,1-dimethylethyl)-6-(trifluoromethyl)pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H24ClF3N4 |
| Molecular Weight | 364.84 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloropropyl Standards
- 10-(3-Chloropropyl)-2-(methylsulfonyl)-10H-phenothiazine (CAS 40051-30-7)
- 3-(3-Chloropropyl)-1-tosyl-1H-indole-5-carbonitrile (CAS 2306261-63-0)
- 3-(3-Chloropropyl)-1,1,1,5,5,5-hexamethyl-3-((trimethylsilyl)oxy)trisiloxane (CAS 18077-31-1)
- 2-(3-chloropropyl)-3-(4-methoxyphenyl)-1-oxo-1,2,3,4-tetrahydro-4-isoquinolinecarboxylic acid (CAS 385383-38-0)
- 10-(3-Chloropropyl)-2-nitro-10H-indolo[3,2-b]quinoline (CAS 214467-43-3)
- 1-(3-Chloropropyl)-3-(3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea (CAS 874301-79-8)
- tris(2-Chloropropyl)phosphate (CAS 6145-73-9)
- Tris-(2-Chloropropyl)Phosphate (CAS 13674-84-5)
Recommended Standards
- 4-(4-Chlorophenyl)-1-(4-fluorophenyl)-5,6,7,8-tetrahydro-2a,4a-diazacyclopenta[cd]azulene (CAS 488812-80-2)
- N-(2-Chlorobenzyl)-5-oxo-4-(thiophen-2-ylmethyl)morpholine-3-carboxamide (CAS 1421445-11-5)
- 3-[(2-Chloro-6-fluorophenyl)methyl]-2,4-bis(propan-2-yloxy)benzaldehyde (CAS 477846-07-4)
- (4-((4-Chlorophenyl)sulfonyl)piperazin-1-yl)(phenyl)methanone (CAS 333757-02-1)
- n-Cyclopentyl-2,3-dihydro-1h-inden-2-amine (CAS 1153820-24-6)
- Isofebrifugine (CAS 32434-44-9)
- 1-[5-fluoro-2-(1H-imidazol-1-yl)phenyl]ethan-1-one (CAS 1019570-58-1)
- 1-(2-Methoxyphenyl)-3-{1-[3-(pyridin-3-yl)-1,2,4-oxadiazol-5-yl]cyclohexyl}urea (CAS 1396809-34-9)
- Thiophene-3-carboximidamide hydrochloride (CAS 51528-02-0)
- 4-bromo-3-methyl-1H-pyrazolo[3,4-b]pyridine (CAS 1638759-60-0)
- 5-(Chloromethyl)-2-methoxy-4-(trifluoromethyl)pyridine (CAS 1211585-00-0)
- 2-Chloro-4-(difluoromethyl)-6-methylnicotinonitrile (CAS 1271473-78-9)
- ethoxy(propan-2-yl)amine hydrochloride (CAS 1909313-11-6)
- Semaglutide impurity 255 (CAS CATO-C4X-2226255)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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