4-Chloro-5-methoxy-2-(trifluoromethyl)quinazoline CAS 219773-96-3
| CAS No. | 219773-96-3 |
| Molecular Formula | C10H6ClF3N2O |
| Molecular Weight | 262.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4-Chloro-5-methoxy-2-(trifluoromethyl)quinazoline (CAS 219773-96-3), a certified reference material (molecular formula C10H6ClF3N2O, MW 262.62 g/mol) for analytical method development and quality control.
Based on its molecular formula C10H6ClF3N2O, 4-Chloro-5-methoxy-2-(trifluoromethyl)quinazoline contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 262.62 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-5-methoxy-2-(trifluoromethyl)quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6ClF3N2O |
| Molecular Weight | 262.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- N-[4-Chloro-2-(trifluoromethyl)phenyl]-2-cyanoacetamide (CAS 1017052-21-9)
- 5-Chloro-6-cyclopropyl-2-hydroxy-4-(trifluoromethyl)nicotinonitrile (CAS 1092352-56-1)
- 3-Chloro-1-(5-(trifluoromethyl)pyridin-2-yl)-1h-pyrazol-4-amine (CAS 1172546-14-3)
- 4-Chloro-1-(5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-3-amine (CAS 1173076-21-5)
- 4-Chloro-1-phenyl-3-(trifluoromethyl)-1h-pyrazol-5-ol (CAS 122431-44-1)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-pyrazol-3-amine (CAS 1242267-93-1)
- 4-Chloro-3-[4-(trifluoromethoxy)phenyl]-1h-pyrazole (CAS 1304255-05-7)
- 4-Chloro-2-(1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl)pyrimidine (CAS 1365940-41-5)
Recommended Standards
- 2-(Chloromethyl)-7-(trifluoromethyl)-3,4-dihydroquinazolin-4-one (CAS 730976-60-0)
- 4-Chloro-6-methoxy-2-(trifluoromethyl)quinazoline (CAS 338739-38-1)
- 2-(Chloromethyl)-5-[3-(trifluoromethyl)phenyl]-1,3,4-oxadiazole (CAS 944897-58-9)
- 4-Chloro-7-methoxy-2-(trifluoromethyl)quinazoline (CAS 951904-99-7)
- 3-Methyl-5-(4-methylpiperazin-2-yl)-1,2,4-oxadiazole (CAS 129594-96-3)
- (S)-Fmoc-2-amino-6-tert-butoxy-hexanoic acid (CAS 1354752-71-8)
- N-(2-aminoethyl)-2-(trifluoromethyl)benzamide hydrochloride (CAS 1171228-13-9)
- 1060809-65-5 4-Amino-6-chloropyridine-2-carbaldehyde DTXSID10704401 (CAS 1060809-65-5)
- Ruxolitinib Impurity 7 (CAS CATO-C4X-20587)
- 【停用，见C4X-187758】Pyridoxine impurity 71 (CAS CATO-C4X-187771)
- 3-Cyclopropyl-1-methyl-4-nitro-1H-pyrazol-5-amine (CAS 1558136-69-8)
- 4-[5-(3,4-Dimethoxyphenyl)-2H-tetrazol-2-yl]piperidine hydrochloride (CAS 1052518-26-9)
- Lasmiditan Impurity 35 (CAS CATO-C4X-247835)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com