(R)-3-(1-aminoethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one CAS 2199389-46-1
| CAS No. | 2199389-46-1 |
| Molecular Formula | C17H15ClN2O |
| Molecular Weight | 298.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(R)-3-(1-aminoethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one (CAS 2199389-46-1) is a high-purity analytical reference standard with the molecular formula C17H15ClN2O and a molecular weight of 298.77 g/mol.
(R)-3-(1-aminoethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one (C17H15ClN2O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (R)-3-(1-aminoethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H15ClN2O |
| Molecular Weight | 298.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related R Standards
- (S)-3-(1-Aminoethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one (CAS 1350643-72-9)
- 5-(2-Aminoethyl)-2-(4-ethoxyphenyl)-4H,5H-pyrazolo[1,5-a]pyrazin-4-one (CAS 1638612-89-1)
- 4-((2-Aminoethyl)amino)-1-nitroacridin-9(10H)-one (CAS 128071-39-6)
- N-(7-(2-Aminoethyl)-6-oxo-6,7-dihydro-1H-purin-2-yl)benzamide (CAS 138753-80-7)
- (S)-2-(1-Aminoethyl)-5-chloro-3-phenylquinazolin-4(3H)-one (CAS 1420627-35-5)
- 1-(2-Aminoethyl)-N,N-diethyl-1H-benzo[d][1,2,3]triazole-6-sulfonamide (CAS 1172828-53-3)
- (R)-2-(1-Aminoethyl)-3-(4-chlorophenyl)pyrido[2,3-d]pyrimidin-4(3H)-one (CAS 1174540-27-2)
- N-(2-aminoethyl)-3-(5-bromofuran-2-yl)-1,2,4-oxadiazole-5-carboxamide (CAS 924871-28-3)
Recommended Standards
- (5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)(phenyl)methanol (CAS 318248-51-0)
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- (3-(4-Chlorophenyl)-1-(p-tolyl)-1H-pyrazol-4-yl)methanol (CAS 36640-60-5)
- 1-(4-Chlorophenyl)-4-(2-methoxyphenyl)-3-methyl-1H-pyrazole (CAS 955964-17-7)
- Ethyl 3-acetyl-2-methylbenzoate (CAS 898747-04-1)
- N,N-Dibenzyl-1-(methylsulfonyl)piperidine-3-carboxamide (CAS 1000949-56-3)
- Ethyl 2-(4-(hydroxymethyl)phenyl)propanoate (CAS 118618-33-0)
- 6,6-(1,3-Phenylenebis(azanediyl))-bis(2,4-di-tert-butylphenol) (CAS 2951-81-7)
- N-((1H-Benzo[d]imidazol-2-yl)methyl)-N-(2-acetamidophenyl)acetamide (CAS 91362-52-6)
- (S)-2-Amino-1-((R)-3-(benzyl(methyl)amino)piperidin-1-yl)propan-1-one (CAS 1401667-70-6)
- 3-Methyl-N-(3-methylbut-2-en-1-yl)-3H-purin-6-amine (CAS 62061-50-1)
- 2-Hydroxy-6-iodobenzenesulfonamide (CAS 913725-56-1)
- 1-(2-Methoxyethyl)-2,3-dihydro-1h-isoindole (CAS 127797-17-5)
- Peptide Impurity 27 (CAS 1350456-68-6)
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