2-Bromo-1-(2-fluoro-4-hydroxyphenyl)ethan-1-one CAS 220131-30-6

Purity 97%+In StockPharmaceutical Standards
CAS No.220131-30-6
Molecular FormulaC8H6BrFO2
Molecular Weight233.03 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Bromo-1-(2-fluoro-4-hydroxyphenyl)ethan-1-one CAS 220131-30-6 chemical structure

Description

CATO manufactures 2-Bromo-1-(2-fluoro-4-hydroxyphenyl)ethan-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

2-Bromo-1-(2-fluoro-4-hydroxyphenyl)ethan-1-one (CAS 220131-30-6) is a high-purity analytical reference standard with the molecular formula C8H6BrFO2 and a molecular weight of 233.03 g/mol.

The molecular framework of 2-Bromo-1-(2-fluoro-4-hydroxyphenyl)ethan-1-one (C8H6BrFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC8H6BrFO2
Molecular Weight233.03 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2019
Halogen ContentF/Br-containing

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