2-Bromo-1-(4-fluoro-2-hydroxyphenyl)ethan-1-one CAS 866863-55-0
| CAS No. | 866863-55-0 |
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution, an aromatic ring system, 2-Bromo-1-(4-fluoro-2-hydroxyphenyl)ethan-1-one is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 233.03 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
2-Bromo-1-(4-fluoro-2-hydroxyphenyl)ethan-1-one (CAS 866863-55-0), molecular formula C8H6BrFO2 and molecular weight 233.03 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Bromo-1-(4-fluoro-2-hydroxyphenyl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6BrFO2 |
| Molecular Weight | 233.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Br-containing |
Related Bromo Standards
- 2-Bromo-4-fluoro-5-methylbenzoic acid (CAS 1003709-39-4)
- 2-Bromo-4-fluoro-6-methylbenzoic Acid (CAS 1003709-47-4)
- 2-Bromo-5-fluoro-4-methylbenzoic acid (CAS 1003709-54-3)
- 3-Bromo-5-fluoro-2-methoxybenzaldehyde (CAS 1009093-60-0)
- 1-(5-Bromo-3-fluoro-2-hydroxyphenyl)ethan-1-one (CAS 1089706-28-4)
- 4-Bromo-2-fluorophenylacetic Acid (CAS 114897-92-6)
- 3-Bromo-2-fluoro-4-methoxybenzaldehyde (CAS 1155877-70-5)
- 3-Bromo-2-fluoro-6-methoxybenzaldehyde (CAS 1160653-94-0)
Recommended Standards
- 2-Bromo-1-(2-fluoro-4-hydroxyphenyl)ethan-1-one (CAS 220131-30-6)
- 2-Bromo-4-fluoro-5-methoxybenzaldehyde (CAS 865186-62-5)
- 2-(3-Bromo-5-fluorophenyl)acetic acid (CAS 202000-99-5)
- 2-Bromo-4-fluorophenyl acetate (CAS 480439-44-9)
- Dimethyl Acetal (CAS 534-15-6)
- N-METHYL-2-FLUORO-4-IODOBENZAMIDE (CAS 1351185-56-2)
- S-(2-(1H-Indol-3-yl)-2-oxoethyl) ethanethioate (CAS 653586-11-9)
- (3-Formylpyridin-2-yl)boronic acid (CAS 1694641-84-3)
- 2-(2,6-dioxo-3-piperidyl)-4-[2-(2-iodoethoxy)ethoxy]isoindoline-1,3-dione (CAS 2581818-53-1)
- 3-(2-Fluorophenyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 23892-21-9)
- Z-D-Glu(OtBu)-OH (CAS 51644-83-8)
- 3-((4-Methoxy-4-methylpentan-2-yl)amino)propan-1-ol (CAS 1038696-36-4)
- 2-Chloro-5-(ethanesulfonyl)benzoic acid (CAS 90649-97-1)
- Prolactin-Releasing Peptide (12-31), rat (CAS 222988-10-5)
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