5-Fluoroorotic acid monohydrate CAS 220141-70-8
| CAS No. | 220141-70-8 |
| Molecular Formula | C5H3FN2O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Fluoroorotic acid monohydrate is closely related to a carbohydrate-derived structure, an amide group, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-Fluoroorotic acid monohydrate (CAS 220141-70-8), molecular formula C5H3FN2O4H2O and molecular weight 192.10 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-Fluoroorotic acid monohydrate (C5H3FN2O4H2O) is characterized by a carbohydrate-derived structure, an amide group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-Fluoroorotic acid monohydrate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H3FN2O4 H2O |
| Molecular Weight | 192.10 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 2019 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoroorotic Standards
Recommended Standards
- 2-(2-(Methoxycarbonyl)-6-(trifluoromethyl)pyridin-4-yl)acetic acid (CAS 1393542-96-5)
- 5-(4-Chlorophenyl)-1-(2-propylpentanoyl)pyrazolidin-3-one (CAS 740812-30-0)
- (Z)-[Amino(4-aminophenyl)methylidene]amino 4-chlorobenzoate (CAS 1373237-01-4)
- 5-Fluoro-n1,n1-dimethylbenzene-1,2-diamine (CAS 1249302-23-5)
- [2-(prop-1-en-2-yl)oxolan-3-yl]methanamine (CAS 1803589-39-0)
- 2,2'-(5-Bromo-1,3-phenylene)diacetic acid (CAS 193010-40-1)
- 16-Hydroxytriptolide (CAS 139713-80-7)
- 5-(Methoxymethyl)-3-(pyridin-2-yl)pyrazolo[1,5-a]pyrimidin-7(1H)-one (CAS 866049-99-2)
- Vonoprazan Impurity 16 (CAS 16133-25-8)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com