2-(3-Fluoro-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione CAS 220460-55-9

Purity 97%+In StockPharmaceutical Standards
CAS No.220460-55-9
Molecular FormulaC13H9FN2O4
Molecular Weight276.22 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(3-Fluoro-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione CAS 220460-55-9 chemical structure

Description

2-(3-Fluoro-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione (CAS 220460-55-9) is a high-purity analytical reference standard with the molecular formula C13H9FN2O4 and a molecular weight of 276.22 g/mol.

Based on its molecular formula C13H9FN2O4, 2-(3-Fluoro-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 276.22 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H9FN2O4
Molecular Weight276.22 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2019
Halogen ContentF-containing
Nitrogen Atoms2

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