5-(Ethoxymethyl)quinolin-8-ol CAS 22049-19-0
| CAS No. | 22049-19-0 |
| Molecular Formula | C12H13NO2 |
| Molecular Weight | 203.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-(Ethoxymethyl)quinolin-8-ol is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
5-(Ethoxymethyl)quinolin-8-ol (CAS 22049-19-0), molecular formula C12H13NO2 and molecular weight 203.24 g/mol, is a CATO reference standard with documented purity and traceability.
5-(Ethoxymethyl)quinolin-8-ol (C12H13NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. Its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(Ethoxymethyl)quinolin-8-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H13NO2 |
| Molecular Weight | 203.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 1 |
Related Ethoxymethyl Standards
- 1-(Ethoxymethyl)quinolin-2(1H)-one (CAS 772398-57-9)
- Ethyl 2-(Ethoxymethyl)-3,3-dimethylbutanoate (CAS 131837-13-3)
- 2-(Ethoxymethyl)isoindoline-1,3-dione (CAS 2860-50-6)
- 2-(Ethoxymethyl)-4-methyl-1,3-thiazole-5-carboxylic acid (CAS 136204-53-0)
- 4-(Ethoxymethyl)-2-methylthiazole-5-carboxylic acid (CAS 1708037-58-4)
- 1-[2-(ethoxymethyl)-4-methyl-1,3-thiazol-5-yl]ethan-1-amine (CAS 1491006-67-7)
- 6-(ethoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (CAS 1443531-68-7)
- 4-(Ethoxymethyl)-6-ethyl-2-hydroxynicotinonitrile (CAS 887574-28-9)
Recommended Standards
- 5-(Dimethylamino)-1-phenyl-1H-pyrazol-3(2H)-one (CAS 62236-00-4)
- 5-(tert-Butyl)phthalimide (CAS 50727-07-6)
- 5-(4-Methoxyphenyl)-5-oxovaleronitrile (CAS 26823-02-9)
- 5,6-Dimethoxy-1-methylisoquinoline (CAS 30836-91-0)
- Methyl (E)-3-(2-chloro-3-(dimethoxymethyl)pyridin-4-yl)acrylate (CAS 1186405-24-2)
- (S)-2-Amino-1-(4-(isopropyl(methyl)amino)piperidin-1-yl)-3-methylbutan-1-one (CAS 1354020-51-1)
- 1-[(3-Chlorophenyl)methoxy]imidazolidine-2,4,5-trione (CAS 339104-02-8)
- 4-Bromo-2-fluoropyrimidine (CAS 1209458-22-9)
- [(2,4-Dichlorophenyl)methyl]hydrazine (CAS 51421-37-5)
- 2-Amino-4-(3-iodophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 337496-56-7)
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- Sulfoaceticacidmonohydrate (CAS 6155-83-5)
- 3,6-Difluoro-2-methylbenzodifluoride (CAS 1803847-29-1)
- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
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