2-Amino-4-(3-iodophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile CAS 337496-56-7
| CAS No. | 337496-56-7 |
| Molecular Formula | C18H17IN2O2 |
| Molecular Weight | 420.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 420.24 g/mol gives 2-Amino-4-(3-iodophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-Amino-4-(3-iodophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (CAS 337496-56-7) is a high-purity analytical reference standard with the molecular formula C18H17IN2O2 and a molecular weight of 420.24 g/mol.
2-Amino-4-(3-iodophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (C18H17IN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, iodine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-Amino-4-(3-iodophenyl)-7,7-dimethyl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H17IN2O2 |
| Molecular Weight | 420.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | I-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 3-Amino-N-(2,4-dichlorophenyl)-6-ethyl-5H,6H,7H,8H-thieno[2,3-b]quinoline-2-carboxamide (CAS 627057-31-2)
- 3-Amino-N-(2,5-dichlorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 445268-85-9)
- 3-Amino-N-(3,5-dichlorophenyl)-6-ethyl-5,6,7,8-tetrahydrothieno[2,3-b]quinoline-2-carboxamide (CAS 625370-26-5)
- 6-Amino-N-(2,6-dichlorophenyl)-4-thia-2-azatricyclo[7.6.0.0^{3,7}]pentadeca-1(9),2,5,7-tetraene-5-carboxamide (CAS 496804-79-6)
- 6-Amino-5-(3-methoxyphenyl)-7-(1-methyl-1H-benzo[d]imidazol-2-yl)-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitrile (CAS 307343-10-8)
- 6-Amino-4-(4-methoxyphenyl)-1,3-diphenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile (CAS 188199-07-7)
- 2-Amino-7,7-dimethyl-1-(3-nitrophenyl)-5-oxo-4-(thiophen-2-yl)-1,4,5,6,7,8-hexahydroquinoline-3-carbonitrile (CAS 311323-43-0)
- 3-Amino-N-(3,5-dimethoxybenzyl)-6-(pyridin-4-yl)thieno[2,3-b]pyridine-2-carboxamide (CAS 445267-42-5)
Recommended Standards
- Propanedioic acid, 2-(6-iodo-3-pyridazinyl)-, 1,3-bis(1,1-dimethylethyl) ester (CAS 1853166-10-5)
- Amiodarone Hydrochloride EP Impurity F (CAS 147030-50-0)
- 8-Iodo-6-phenylnaphtho[2,1-b]benzofuran (CAS 1668553-52-3)
- Nintedanib Impurity 143 (CAS CATO-C4X-1814143)
- Methyl 3-(thiophen-3-yl)propanoate (CAS 179932-05-9)
- (E)-2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((dimethylamino)methylene)-2-methylhydrazine-1-carboxamide (CAS 321433-38-9)
- N-[5-[2-[[2-(5-Amino-1,3,4-thiadiazol-2-yl)ethyl]thio]ethyl]-1,3,4-thiadiazol-2-yl]-benzeneacetamide (CAS 1415397-13-5)
- N-(4-Hydroxyphenylacetyl)-spermine (CAS 130210-32-1)
- Methyl 2-amino-5-(tert-butyl)thiophene-3-carboxylate (CAS 216574-71-9)
- Rilpivirine Impurity 1 HCl (CAS 500287-94-5(free base))
- 4-(4-Amino-2-methyl-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester (CAS 138227-69-7)
- Methyl 4-{[(E)-2-[5-acetyl-3-(4-methylbenzamido)-2-oxo-2H-pyran-6-yl]ethenyl]amino}benzoate (CAS 338392-07-7)
- N-(4-ethoxyphenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 303091-65-8)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com