2,4,6-trichloro-8-fluoro-quinazoline CAS 2205387-69-3
| CAS No. | 2205387-69-3 |
| Molecular Formula | C8H12Cl3FN2 |
| Molecular Weight | 261.55 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,4,6-trichloro-8-fluoro-quinazoline is closely related to a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,4,6-trichloro-8-fluoro-quinazoline (CAS 2205387-69-3), molecular formula C8H12Cl3FN2 and molecular weight 261.55 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,4,6-trichloro-8-fluoro-quinazoline (C8H12Cl3FN2) is characterized by a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,4,6-trichloro-8-fluoro-quinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H12Cl3FN2 |
| Molecular Weight | 261.55 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related trichloro Standards
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Why CATO?
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