Ticagrelor Impurity 63 CAS 2205903-74-6
| CAS No. | 2205903-74-6 |
| Molecular Formula | C27H42N6O8S |
| Molecular Weight | 610.72 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ticagrelor Impurity 63.
As a process- or degradation-related impurity, Ticagrelor Impurity 63 (CAS 2205903-74-6, C27H42N6O8S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Ticagrelor Impurity 63 (C27H42N6O8S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 610.72 g/mol, it falls into the high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Ticagrelor Impurity 63 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H42N6O8S |
| Molecular Weight | 610.72 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related Ticagrelor Standards
- Ticagrelor Impurity 78 (CAS CATO-C4X-109378)
- Ticagrelor Impurity 40 (CAS CATO-C4X-109340)
- Ticagrelor Impurity 51 (CAS 1882095-51-3)
- Ticagrelor Nitroso EP Impurity C (CAS CATO-C4X-1093163)
- Ticagrelor Impurity 170 (CAS CATO-C4X-1093170)
- Ticagrelor Impurity 144 (CAS 274693-25-3)
- Ticagrelor Impurity 147 (CAS CATO-C4X-1093147)
- Ticagrelor Impurity 180 (CAS CATO-C4X-1093180)
Recommended Standards
- 9025-24-5 Carboxypeptidase B from human pancreas Carboxypeptidase B from porcine pancreas Carboxypeptidase B, AEBSF treated from hog pancreas Peptidyl-L-Lysine[L-arginine] hydrolase Peptidyl-L-lysine(L-arginine) hydrolase Protaminase Protaminase, AEBSF treated (CAS 9025-24-5)
- Suc-Ala-Ala-Pro-Phe-SBzl (CAS 80651-95-2)
- 83144-89-2 N,N,N',N'-Tetrakis(2-benzimidazolylmethyl)-1,3-diaminopropan-2-ol N,N,N',N'-Tetrakis(2-benzimidazolylmethyl)-2-hydroxy-1,3-propanediamine N,N,N',N'-Tetrakis[(2-benzimidazolyl)methyl]-2-hydroxy-1,3-diaminopropane (CAS 83144-89-2)
- [1(1S)]-2,3:4,5-Di-O-cyclohexylidene-6-O-(phenylmethyl)-D-myo-Inositol 4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carboxylate (CAS 108340-80-3)
- Tacrolimus EP Impurity C (CAS CATO-C4X-130025)
- Bilastine Impurity 78 (CAS 1638785-22-4)
- Letermovir Impurity 53 (CAS CATO-C4X-291553)
- 4-Chloro-[1,1'-biphenyl]-3-carboxylic acid (CAS 855207-59-9)
- 2-Amino-4-(benzyloxy)phenol (CAS 102580-07-4)
- 5,7-Difluorobenzofuran-3(2h)-one (CAS 939759-28-1)
- 3,5-Difluoro-4-(1h-pyrazol-1-yl)benzaldehyde (CAS 1342028-33-4)
- (S)-4-Amino-2-((ethoxycarbonyl)amino)-4-oxobutanoic acid (CAS 16639-91-1)
- 3,6-Dimethyl-4H-pyrano[4,3-c]isoxazol-4-one (CAS 28495-02-5)
- Semaglutide Impurity 130 (CAS 1188328-40-6)
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