3-Bromo-8-methoxy-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one CAS 2206365-13-9
| CAS No. | 2206365-13-9 |
| Molecular Formula | C10H6BrF3N2O2 |
| Molecular Weight | 323.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Bromo-8-methoxy-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (CAS 2206365-13-9) is a high-purity analytical reference standard with the molecular formula C10H6BrF3N2O2 and a molecular weight of 323.07 g/mol.
3-Bromo-8-methoxy-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one (C10H6BrF3N2O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Bromo-8-methoxy-2-(trifluoromethyl)-4H-pyrido[1,2-a]pyrimidin-4-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H6BrF3N2O2 |
| Molecular Weight | 323.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- Methyl 6-bromo-8-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate (CAS 1121058-16-9)
- 6-Bromo-2-(trifluoromethyl)imidazo[1,2-a]pyridine-3-carbohydrazide (CAS 1427460-87-4)
- 4-Bromo-6-methoxy-2-(trifluoromethyl)-1,5-naphthyridin-3-ol (CAS 1565779-86-3)
- 8-Bromo-1-methyl-6-(trifluoromethyl)quinoxaline-2,3(1H,4H)-dione (CAS 1864016-15-8)
- 7-Bromo-8-methyl-6-(trifluoromethyl)quinazoline-2,4(1H,3H)-dione (CAS 2803281-34-5)
- Methyl 3-bromo-6-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxylate (CAS 952800-37-2)
- 1-(4-Bromo-2,3,5,6-tetrafluorophenyl)-3,5-dimethyl-1H-pyrazole (CAS 1004018-33-0)
- 7-Bromo-5-(pentafluoro-λ6-sulfanyl)-1H-benzo[d]imidazole (CAS 1432075-84-7)
Recommended Standards
- 5-(Chlorosulfonyl)-2-(trifluoromethoxy)benzoyl chloride (CAS 2138246-10-1)
- 4-Bromo-2-fluorophenyl trifluoromethanesulfonate (CAS 872054-03-0)
- 3-Iodo-2,5,6-trimethoxyisonicotinaldehyde (CAS 1383788-27-9)
- 2-Bromo-4-fluorophenyl trifluoromethanesulfonate (CAS 885276-20-0)
- 2,6-Bis[(4R)-4,5-dihydro-4-tricyclo[3.3.1.13,7]dec-1-yl-2-oxazolyl]pyridine (CAS 934384-49-3)
- Methyl 2,4-dicyclopentylquinoline-3-carboxylate (CAS 753487-72-8)
- Fmoc-Pen(Trt)-OH (CAS 201531-88-6)
- Vildagliptin Impurity 77 (CAS CATO-C4X-110077)
- 3-Benzoyl-1,3-thiazolidine-2-thione (CAS 70326-37-3)
- O-guanidinohomoserine compound with sulfuric acid (1:1) (CAS 1078611-11-6)
- Tert-butyl (3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)carbamate (CAS 1417637-90-1)
- 2-Amino-2-(4-bromophenyl)propan-1-ol (CAS 1179700-68-5)
- Tris(acetonitrile)pentamethylcyclopentadienylruthenium(II) hexafluorophosphate 99604-67-8 TRIS(ACETONITRILE)PENTAMETHYLCYCLOPENTADIENYLRUTHENIUM(I) HEXAFLUOROPHOSPHATE;TRIS(ACETONITRILE)PENTAMETHYLCYCLOPENTADIENYLRUTHENIUM(II) HEXAFLUOROPHOSPHATE SC10292 (CAS 99604-67-8)
- endo-Ser39-Tirzepatide (CAS CATO-CPTD788935)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com