Glycopyrronium Bromide impurity 12 CAS 22065-57-2
| CAS No. | 22065-57-2 |
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Glycopyrronium Bromide impurity 12 (CAS 22065-57-2), a pharmacopoeial impurity reference standard (molecular formula C10H10N2O2, MW 190.20 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Glycopyrronium Bromide impurity 12 (C10H10N2O2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 190.20 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H10N2O2 |
| Molecular Weight | 190.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Nitrogen Atoms | 2 |
Related Glycopyrronium Standards
- Glycopyrronium Bromide EP Impurity K (CAS 3900-93-4)
- Glycopyrronium Bromide EP Impurity M (CAS 5422-88-8)
- Glycopyrronium Bromide EP Impurity O (CAS 618-88-2)
- Glycopyrronium Bromide EP Impurity H (CAS 15206-55-0)
- Glycopyrronium Bromide EP Impurity J (CAS 427-49-6)
- Glycopyrronium Bromide EP Impurity B (CAS 611-73-4)
- Glycopyrronium Bromide Impurity 21 (CAS CATO-C4X-181721)
- Glycopyrronium Bromide EP Impurity L (CAS 64471-47-2)
Recommended Standards
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- Flupentixol Impurity 7 (E and Z Mixture) (CAS CATO-C4X-18957)
- Vazegepant Impurity 42 (CAS CATO-C4X-320042)
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- 3-Nitro-N-(4h-1,2,4-triazol-4-yl)benzamide (CAS 326619-24-3)
- Ethyl 2-phenyl-4-(m-tolylthio)pyrimidine-5-carboxylate (CAS 477854-58-3)
- (+)-Germacrone-4,5-epoxide (CAS 92691-35-5)
- 3-(Trifluoromethoxy)azetidine (CAS 1422766-39-9)
- 1-Chloro-2-methoxy-4,5-dimethylbenzene (CAS 38946-57-5)
- Semaglutide Impurity 139 (CAS CATO-C4X-2226139)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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