Lifitegrast Impurity 19 CAS 1289646-90-7
| CAS No. | 1289646-90-7 |
| Molecular Formula | C11H10O3 |
| Molecular Weight | 190.20 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Lifitegrast Impurity 19.
Lifitegrast Impurity 19 (CAS 1289646-90-7) is a certified pharmaceutical impurity reference standard with the molecular formula C11H10O3 and a molecular weight of 190.20 g/mol.
Structurally, Lifitegrast Impurity 19 (C11H10O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 190.20 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lifitegrast Impurity 19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H10O3 |
| Molecular Weight | 190.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
Related Lifitegrast Standards
- Lifitegrast Impurity N68 (CAS 89315-56-0)
- Lifitegrast Impurity N60 (CAS 933752-32-0)
- Lifitegrast Impurity 168 (CAS CATO-C4X-2409168)
- Lifitegrast Impurity 42 (CAS 588703-29-1)
- Lifitegrast Impurity 108 (CAS CATO-C4X-2409108)
- Lifitegrast Impurity 109 (CAS CATO-C4X-2409109)
- Lifitegrast Impurity 149 (CAS CATO-C4X-2409149)
- Lifitegrast Impurity 10 (CAS 77095-51-3)
Recommended Standards
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- Ribociclib Impurity 8 (CAS 2460734-07-8)
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- 102389-88-8 Trans (+/-)-pyrrolidine-3,4-dicarboxylic acid dimethyl ester (CAS 102389-88-8)
- tert-Butyl (1R*,4R*)-4-(neopentylamino)cyclohexylcarbamate (CAS 1286273-27-5)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com