2-(4-Phenylpiperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)acetamide CAS 329080-47-9
| CAS No. | 329080-47-9 |
| Molecular Formula | C19H20F3N3O |
| Molecular Weight | 363.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(4-Phenylpiperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)acetamide is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(4-Phenylpiperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 329080-47-9) is a high-purity analytical reference standard with the molecular formula C19H20F3N3O and a molecular weight of 363.38 g/mol.
2-(4-Phenylpiperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)acetamide (C19H20F3N3O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Phenylpiperazin-1-yl)-N-(3-(trifluoromethyl)phenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H20F3N3O |
| Molecular Weight | 363.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Phenylpiperazin Standards
- 2-(4-Phenylpiperazin-1-yl)-N-(4-(trifluoromethyl)phenyl)acetamide (CAS 720667-94-7)
- 1-(4-Phenylpiperazin-1-yl)-2-(3-(trifluoromethyl)phenoxy)ethan-1-one (CAS 866153-13-1)
- 3-(3-(4-Phenylpiperazin-1-yl)propyl)quinazoline-2,4(1H,3H)-dione (CAS 2208-51-7)
- 2-((4-Phenylpiperazin-1-yl)methyl)-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one (CAS 139047-55-5)
- n-(4-((4-Phenylpiperazin-1-yl)sulfonyl)phenyl)acetamide (CAS 321531-92-4)
- N-(3-(4-Phenylpiperazin-1-yl)propyl)-2-(o-tolyloxy)acetamide (CAS 1049375-34-9)
- 1-Methyl-4-{5-[(4-phenylpiperazin-1-yl)methyl]-1,3-thiazol-2-yl}piperazine (CAS 478079-09-3)
- 1-Phenyl-4-(4-phenylpiperazin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine (CAS 393845-64-2)
Recommended Standards
- (Z)-[(4-Fluorophenyl)[2-(4-methylphenyl)cyclopropyl]methylidene]amino furan-2-carboxylate (CAS 338749-06-7)
- (5-(4-Fluorobenzyl)-2,4-dihydroxyphenyl)(isoindolin-2-yl)methanone (CAS 2134571-29-0)
- 2-[4-(4-Methoxybenzenesulfonyl)-3,4-dihydro-2H-1,4-benzoxazin-3-yl]acetic acid (CAS 865657-74-5)
- (2R,3S,4R,5R,6S)-5-Acetamido-2-(acetoxymethyl)-6-mercaptotetrahydro-2H-pyran-3,4-diyl diacetate (CAS 51450-09-0)
- (R)-3,3,3-Trifluoro-1-(4-(trifluoromethyl)phenyl)propan-1-amine (CAS 1259943-93-5)
- 2-(2,6-Difluorophenyl)ethanol (CAS 168766-16-3)
- (1-Cinnamylpiperidin-4-yl)methanol (CAS 1311997-24-6)
- 4'-tert-Butyldimethylsilyl-6-hydroxy Raloxifene (CAS 174264-46-1)
- Methyl 3-(3-fluoro-4-methylphenyl)-5-(trifluoromethyl)benzoate (CAS 1820718-40-8)
- 2-Bromo-6-(trifluoromethyl)pyridin-4-amine (CAS 1806857-87-3)
- 1,2-Di(piperidin-1-yl)ethane-1,2-dithione (CAS 24528-76-5)
- 3,3,3-Trifluoro-2,2-dimethylpropane-1-sulfonyl chloride (CAS 1783625-32-0)
- N-(2-Methoxyphenyl)-7-phenyl-1,4-thiazepane-4-carboxamide (CAS 1797028-88-6)
- Semaglutide impurity 244(Fmoc-His(Fmoc)-Aib-OH) (CAS CATO-C4X-2226244)
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