2-[2-(4-fluorophenyl)-1,3-oxazol-4-yl]acetic acid CAS 22091-43-6

Purity 97%+In StockPharmaceutical Standards
CAS No.22091-43-6
Molecular FormulaC11H8FNO3
Molecular Weight221.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-[2-(4-fluorophenyl)-1,3-oxazol-4-yl]acetic acid CAS 22091-43-6 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

CATO supplies 2-[2-(4-fluorophenyl)-1,3-oxazol-4-yl]acetic acid (CAS 22091-43-6), a certified reference material (molecular formula C11H8FNO3, MW 221.18 g/mol) for analytical method development and quality control.

The molecular framework of 2-[2-(4-fluorophenyl)-1,3-oxazol-4-yl]acetic acid (C11H8FNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC11H8FNO3
Molecular Weight221.18 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963
Halogen ContentF-containing
Nitrogen Atoms1

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