Methyl 2-(4,5-dichloro-6-oxopyridazin-1(6H)-yl)acetate CAS 220967-67-9
| CAS No. | 220967-67-9 |
| Molecular Formula | C7H6Cl2N2O3 |
| Molecular Weight | 237.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Methyl 2-(4,5-dichloro-6-oxopyridazin-1(6H)-yl)acetate.
Methyl 2-(4,5-dichloro-6-oxopyridazin-1(6H)-yl)acetate (CAS 220967-67-9), molecular formula C7H6Cl2N2O3 and molecular weight 237.04 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl 2-(4,5-dichloro-6-oxopyridazin-1(6H)-yl)acetate (C7H6Cl2N2O3) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Methyl 2-(4,5-dichloro-6-oxopyridazin-1(6H)-yl)acetate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H6Cl2N2O3 |
| Molecular Weight | 237.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
- 2,3-Dichloro-4-hydroxy-5-methoxybenzoic acid (CAS 108544-97-4)
- (4,5-Dichloro-6-oxopyridazin-1(6H)-yl)methyl acetate (CAS 97137-15-0)
- 2-(2,4-Dichloro-5-hydroxyphenoxy)acetic Acid (CAS 2639-79-4)
- 2,6-Dichloro-3-hydroxy-4-methoxybenzoic acid (CAS 773870-39-6)
- 3,5-Dichloro-2-hydroxy-6-methoxybenzoic acid (CAS 89894-57-5)
- Methyl 2,6-dichloro-5-methoxypyrimidine-4-carboxylate (CAS 878650-31-8)
- Methyl 4,5-dichloro-2,3-dihydroxybenzoate (CAS 819800-61-8)
- 2-(4,6-Dichloro-2-(difluoromethyl)pyridin-3-yl)acetonitrile (CAS 1803670-91-8)
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