2-Amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile CAS 220986-38-9
| CAS No. | 220986-38-9 |
| Molecular Formula | C16H10ClFN2O3 |
| Molecular Weight | 332.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 2-Amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
2-Amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile (CAS 220986-38-9) is a high-purity analytical reference standard with the molecular formula C16H10ClFN2O3 and a molecular weight of 332.71 g/mol.
The molecular framework of 2-Amino-4-(2-chloro-6-fluorophenyl)-7-methyl-5-oxo-4H,5H-pyrano[4,3-b]pyran-3-carbonitrile (C16H10ClFN2O3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C16H10ClFN2O3 |
| Molecular Weight | 332.71 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Amino Standards
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Recommended Standards
- (Z)-(1-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-imidazol-4-yl}ethylidene)(methoxy)amine (CAS 250714-17-1)
- Ethyl 1-(4-chloro-3-(trifluoromethyl)benzyl)-1H-imidazole-4-carboxylate (CAS 1260655-20-6)
- N-[2-Chloro-4-(methoxymethyl)-6-methylquinolin-7-yl]-2,2,2-trifluoroacetamide (CAS 866050-47-7)
- 2-Methoxy-5-(pentafluoro-lambda6-sulfanyl)benzenesulfonyl chloride (CAS 1706447-05-3)
- Methyl (2E)-3-(dimethylamino)-2-(4-methoxybenzenesulfonyl)prop-2-enoate (CAS 1785853-92-0)
- 3,3-Dimethyltetrahydro-2H-pyran-4-carboxylic acid (CAS 1780025-53-7)
- Methyl 5-amino-3-chloro-4-methylthiophene-2-carboxylate (CAS 778611-10-2)
- Empagliflozin impurity 267 (CAS CATO-C4X-1065267)
- Ethyl 4-amino-5-carbamoylisothiazole-3-carboxylate (CAS 890094-03-8)
- 2-Hydroxy-3-phenylbutanoic acid (CAS 91061-47-1)
- Vericiguat Impurity 41 (CAS CATO-C4X-289641)
- Methyl 2-(cyanomethanesulfonyl)acetate (CAS 214691-87-9)
- 5-Acetyl-1,3-dimethyl-1H-benzo[d]imidazol-2(3H)-one (CAS 64826-44-4)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com