Orforglipron Impurity 52 CAS 2212022-57-4
| CAS No. | 2212022-57-4 |
| Molecular Formula | C26H25F2N7O |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C26H25F2N7OHCl, Orforglipron Impurity 52 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 525.99 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Orforglipron Impurity 52 (CAS 2212022-57-4) is a certified pharmaceutical impurity reference standard with the molecular formula C26H25F2N7OHCl and a molecular weight of 525.99 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H25F2N7O HCl |
| Molecular Weight | 525.99 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 7 |
Related Orforglipron Standards
- Orforglipron impurity 36 (CAS 1092961-07-3)
- Orforglipron Impurity 43 (CAS 2025595-61-1(free base))
- Orforglipron Impurity 54 (CAS 210536-89-3)
- Orforglipron impurity 127 (CAS 2203400-61-5)
- Orforglipron Impurity 60 (CAS 2212020-29-4)
- Orforglipron (CAS 2212020-52-3)
- Orforglipron impurity 121 (CAS 2212021-39-9)
- Orforglipron impurity 23 (CAS 2212021-40-2)
Recommended Standards
- Erlotinib Impurity 20 (CAS 938185-06-9)
- Rocuronium impurity 69 (CAS CATO-C4X-124269)
- Tetrabenazine Impurity 64 (CAS 282721-32-8 (non-labelled))
- Betacarotene impurity 7 (CAS CATO-C4X-28157)
- Methyl 3-{[(2-chlorophenyl)methyl]amino}butanoate (CAS 1026959-14-7)
- 2-(3-Bromo-2,4,6-trimethylphenyl)acetic acid (CAS 944-82-1)
- 4-(3-(4-Chlorophenyl)-1H-1,2,4-triazol-5-yl)pyridine (CAS 36646-40-9)
- 5-(4-Chlorophenyl)-4H-1,2,4-triazole-3-carbaldehyde (CAS 26899-27-4)
- 1-((S)-2-hydroxy-1-phenylethyl)-3-((S)-(6-methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methyl)urea (CAS 1639930-41-8)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com