2-Chloro-6-phenyl-4-(trifluoromethyl)pyridine CAS 22123-13-3

Purity 97%+In StockPharmaceutical Standards
CAS No.22123-13-3
Molecular FormulaC12H7ClF3N
Molecular Weight257.64 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-6-phenyl-4-(trifluoromethyl)pyridine CAS 22123-13-3 chemical structure

Description

The occurrence of 2-Chloro-6-phenyl-4-(trifluoromethyl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-Chloro-6-phenyl-4-(trifluoromethyl)pyridine (CAS 22123-13-3), molecular formula C12H7ClF3N and molecular weight 257.64 g/mol, is a CATO reference standard with documented purity and traceability.

2-Chloro-6-phenyl-4-(trifluoromethyl)pyridine (C12H7ClF3N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2-Chloro-6-phenyl-4-(trifluoromethyl)pyridine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H7ClF3N
Molecular Weight257.64 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1963
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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