3-(2-Chloro-5-(trifluoromethyl)phenyl)pyridine CAS 4393-94-6

Purity 97%+In StockPharmaceutical Standards
CAS No.4393-94-6
Molecular FormulaC12H7ClF3N
Molecular Weight257.64 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(2-Chloro-5-(trifluoromethyl)phenyl)pyridine CAS 4393-94-6 chemical structure

Description

The occurrence of 3-(2-Chloro-5-(trifluoromethyl)phenyl)pyridine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 3-(2-Chloro-5-(trifluoromethyl)phenyl)pyridine (CAS 4393-94-6), a certified reference material (molecular formula C12H7ClF3N, MW 257.64 g/mol) for analytical method development and quality control.

The molecular framework of 3-(2-Chloro-5-(trifluoromethyl)phenyl)pyridine (C12H7ClF3N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H7ClF3N
Molecular Weight257.64 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1958
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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