4B-(4-chlorophenyl)-5,11-dihydro-4bH-benzo[4,5]imidazo[2,1-a]isoindole CAS 22131-99-3
| CAS No. | 22131-99-3 |
| Molecular Formula | C20H15ClN2 |
| Molecular Weight | 318.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 4B-(4-chlorophenyl)-5,11-dihydro-4bH-benzo[4,5]imidazo[2,1-a]isoindole (CAS 22131-99-3), a certified reference material (molecular formula C20H15ClN2, MW 318.80 g/mol) for analytical method development and quality control.
4B-(4-chlorophenyl)-5,11-dihydro-4bH-benzo[4,5]imidazo[2,1-a]isoindole (C20H15ClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H15ClN2 |
| Molecular Weight | 318.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
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