4-(2-Chlorophenyl)-N-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine CAS 852388-96-6
| CAS No. | 852388-96-6 |
| Molecular Formula | C16H12ClFN2S |
| Molecular Weight | 318.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(2-Chlorophenyl)-N-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine.
4-(2-Chlorophenyl)-N-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine (CAS 852388-96-6) is a high-purity analytical reference standard with the molecular formula C16H12ClFN2S and a molecular weight of 318.80 g/mol.
Structurally, 4-(2-Chlorophenyl)-N-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine (C16H12ClFN2S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 318.80 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(2-Chlorophenyl)-N-[(4-fluorophenyl)methyl]-1,3-thiazol-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12ClFN2S |
| Molecular Weight | 318.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 6'-Bromo-2H-[1,2'-bipyridin]-2-one (CAS 959237-86-6)
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- 4-Bromo-1,1-difluorobut-1-ene (CAS 147804-02-2)
- Des-Gly34-Tirzepatide (CAS CATO-CPTD788940)
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