3-Oxo-2,3-dihydrobenzo[d]isothiazole-5-carboxylic acid 1,1-dioxide CAS 221446-00-0
| CAS No. | 221446-00-0 |
| Molecular Formula | C8H5NO5S |
| Molecular Weight | 227.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 3-Oxo-2,3-dihydrobenzo[d]isothiazole-5-carboxylic acid 1,1-dioxide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 3-Oxo-2,3-dihydrobenzo[d]isothiazole-5-carboxylic acid 1,1-dioxide (CAS 221446-00-0), a certified reference material (molecular formula C8H5NO5S, MW 227.19 g/mol) for analytical method development and quality control.
Based on its molecular formula C8H5NO5S, 3-Oxo-2,3-dihydrobenzo[d]isothiazole-5-carboxylic acid 1,1-dioxide contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 227.19 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H5NO5S |
| Molecular Weight | 227.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2020 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Oxo Standards
- 3-Oxo-2,3-dihydrobenzo[d]isothiazole-6-carboxylic acid 1,1-dioxide (CAS 90779-46-7)
- 2,3-Dihydrobenzo[g]quinoline-4,5,10(1H)-trione (CAS 6566-47-8)
- Methyl 1,3-dihydrobenzo[c]isothiazole-6-carboxylate 2,2-dioxide (CAS 1455471-64-3)
- 1-Methyl-1,3-dihydrobenzo[c]isothiazole-6-carboxylic acid 2,2-dioxide (CAS 2866498-37-3)
- 5-Methyl-2,3-dihydrobenzo[b]thiophene-2-carboxylic acid 1,1-dioxide (CAS 1893315-30-4)
- Methyl 1,3-dihydrobenzo[c]thiophene-5-carboxylate 2,2-dioxide (CAS 893566-62-6)
- 7-Methyl-1,2-dihydrobenzo[g]quinoxaline-5,10-dione (CAS 681831-63-0)
- 2,3-Dihydrobenzo[b][1,4]oxathiine-2-carboxylic acid 4,4-dioxide (CAS 1251923-88-2)
Recommended Standards
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- 1-(Dimethoxymethyl)-3,5-dimethoxybenzene (CAS 59276-34-5)
- Ethyl 3-(((((4-chlorobenzyl)oxy)amino)methylene)amino)-4-methoxythieno[2,3-b]pyridine-2-carboxylate (CAS 341966-57-2)
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- 1-((Benzyloxy)carbonyl)-3-hydroxypyrrolidine-2-carboxylic acid (CAS 57621-07-5)
- Glucagon (19-29) (human, rat, porcine) (CAS 64790-15-4)
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