5-(Acetylamino)-2-ethoxy-benzenesulfonyl fluoride CAS 22191-76-0
| CAS No. | 22191-76-0 |
| Molecular Formula | C10H12FNO4S |
| Molecular Weight | 261.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 261.27 g/mol gives 5-(Acetylamino)-2-ethoxy-benzenesulfonyl fluoride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 5-(Acetylamino)-2-ethoxy-benzenesulfonyl fluoride (CAS 22191-76-0), a certified reference material (molecular formula C10H12FNO4S, MW 261.27 g/mol) for analytical method development and quality control.
5-(Acetylamino)-2-ethoxy-benzenesulfonyl fluoride (C10H12FNO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-(Acetylamino)-2-ethoxy-benzenesulfonyl fluoride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H12FNO4S |
| Molecular Weight | 261.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1963 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Acetylamino Standards
- 1-[4-(Acetylamino)phenyl]-5-oxopyrrolidine-3-carboxylic acid (CAS 133749-16-3)
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- 5-ACetyl-2-acetylamino-4-methyl-thiophene-3-carboxylic acid methyl ester (CAS 4651-88-1)
- 2'-(Acetylamino)[1,1'-biphenyl]-4-carboxylic acid (CAS 854236-96-7)
- 4-acetylamino-2,5-dimethyl-benzene-1-sulfonyl chloride (CAS 13632-08-1)
- N-(4-Acetylamino-3-methyl-phenyl)-2-chloro-propionamide (CAS 500188-25-0)
- N-[3-(Acetylamino)-2,4-dimethylbenzyl]-2-chloroacetamide (CAS 519041-85-1)
Recommended Standards
- 4-Hydroxybenzo[c]acridin-3(12H)-one (CAS 83538-80-1)
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- 5-(Benzo[d][1,3]dioxol-5-yl)-3-(((2-methoxyphenyl)amino)methyl)-1,3,4-oxadiazol-2(3H)-one (CAS 73484-48-7)
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