2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride CAS 2222114-23-8
| CAS No. | 2222114-23-8 |
| Molecular Formula | C17H17FN4O4 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride (CAS 2222114-23-8), molecular formula C17H17FN4O4HCl and molecular weight 396.80 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(2,6-Dioxopiperidin-3-yl)-5-fluoro-6-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride (C17H17FN4O4HCl) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H17FN4O4 HCl |
| Molecular Weight | 396.80 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Dioxopiperidin Standards
- 2-(2,6-Dioxopiperidin-3-yl)-1-oxoisoindoline-5-carbonitrile (CAS 1010100-21-6)
- 3-(2,6-Dioxopiperidin-1-yl)benzoic acid (CAS 140213-08-7)
- N-(2,6-dioxopiperidin-3-yl)methanesulfonamide (CAS 1416437-99-4)
- 2-(2,6-Dioxopiperidin-1-yl)ethane-1-sulfonic acid (CAS 1417695-29-4)
- 2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindoline-5-carbaldehyde (CAS 1447701-63-4)
- 3-[(2,6-dioxopiperidin-3-yl)carbamoyl]propanoic acid (CAS 1466827-81-5)
- 2-(2,6-dioxopiperidin-1-yl)acetic acid (CAS 147104-12-9)
- N-(2,6-dioxopiperidin-3-yl)-2-methoxyacetamide (CAS 1482069-14-6)
Recommended Standards
- 1-(Benzyloxy)-4-methylpyrrolidin-2-one (CAS 130865-67-7)
- 5-(4-Ethylphenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid (CAS 678543-10-7)
- 1452577-32-0 1-[3-(Trifluoromethyl)phenyl]-2,3,4,9-tetrahydro-1H-beta-carboline-3-carboxylic acid acetate MFCD27756430 (CAS 1452577-32-0)
- 2-(2-(4-Chloro-3-fluorophenoxy)ethyl)-1,3-dioxane (CAS 1443354-21-9)
- 2-Hydroxy-1-(1-piperazinyl)-1-propanone (CAS 100500-89-8)
- 2,6-Dinitrobenzene-1,4-diamine (CAS 67382-08-5)
- 2-(Tetrahydro-2H-pyran-2-yl)phenol (CAS 40324-54-7)
- 3-(4-Ethylphenyl)-3-(1-oxoisoindolin-2-yl)propanoic acid (CAS 439096-97-6)
- 4-Bromo-N-ethyl-3-methoxybenzamide (CAS 1072944-41-2)
- Semaglutide impurity 251 (CAS CATO-C4X-2226251)
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